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What are the major functions of calcium?
Bone structure mainly
- blood clotting
- nerve impulse transmission
- muscle contraction
What is the most abundant mineral in the body?
Calcium
Y/N: does testing calcium in the blood indicate status of calcium in the body?
NO
T/f: there is tight homeostatic control of calcium in the blood
true
the thyroid gland secretes more calcitonin which:
inhibits calc release from the bones
what does the parathyroid hormone do? (3)
1. stims calcium release from the bone
2. stims calcium reabsorption by kidneys
3. activates vitamin D results in increased intestinal absorption from your diet
which hormone is responsible for lowering blood calcium levels?
calcitonin
which annual incidence of injury is the largest between stroke, breast cancer, heart attack and osteoporotic fracture
osteoporotic fracture
what is osteoporosis?
poor bone density and structure, bones break with "low energy" input
osteoporosis causes
lack of bone accrual during growth
bone loss with age or medications
risk factors that can lead to osteoporosis
lack of loading (weights),
poor nutrition,
genetics,
smoking, being a female
what percent of osteo hip fractures result in death?
30%
When is calcium retention maximal in adolescent girls?
1300mg/d
T/F if calcium supplementation is not maintained, you will at first gain bone mineral density, but it will be transient
True
Impact exercise is good for_____
bone mineral density
When is calcium retention maximal in adolescent boys?
1140mg/d
when is 90% of peak bone density achieved
age 18-20
What are some calcium food sources
- milk and dairy products
- fortified foods (ex: orange juice, waffles, soy drinks)
- bones in canned fish
- green vegetables (must eat lots)
- tofu (only if "Ca processed")
What are some factors that increase the risk of low bone strength
- high sodium intake (Na in, Ca out)
- phytate (wheat, bran, beans, seeds, nuts, soy isolates)
- oxalate (rhubarb, beets, okra, spinach...)
- fluoride
Exercise for bones should be:
fast and dynamic
What are some examples of exercise for bones
- jumping (high impact)
- soccer (odd directional loading)
- rapid loading, not slow of isometric (weight training)
How many mg of calcium does the average young adult woman need per day
1000
What interferes with calcium absorption
phytates and oxalates
spinach contains notable amounts of calcium and ___ the latter nutrient of ____
oxalate, increase
T/F most Canadians consume more than enough P but less than the UL
True, it is not a nutrient of concern
Seeds and grains store P as
Phytate
We need ____ (enzyme) to digest phytate
phytase
Total body strores of Fe for men
600-1000mg
Total body stores of Fe for Women
200-300mg
T/F the body recycles little of the iron it gets
False - it recycles most
What are the storage forms of iron found mostly in the liver
ferritin and hemosiderin
Most iron is transported as ____ and transferred to red blood cells
transferrin
What is the best mirror of iron status in the body
ferritin
how many cups of kale are needed to meet the calcium requirement for a teenaged y/o woman? (180 mg/cup)
A. 4
B. 5
C. 6
D. 7
D. 7
which mineral is the second most abundant in the body next to calcium?
phosphorus
T/F: phosphorus helps to form parts of DNA and RNA
true
is phosphorus a component of ATP?
yes (adenoseine triPHOSPHATE)
what is the most readily absorbed type of iron?
heme iron
what food sources can nonheme iron be found in?
plant-based foods
what 3 minerals decrease iron absorption?
calcium and phosphorus, phytates
what is a less readily absorbed type of iron?
nonheme iron
what food sources can heme iron be found in?
fish, meat poultry
T/F: Phosphorus helps maintain a normal pH
true
what are the main functions of iron in the body?
oxygen transport and cofactor for enzymes, brain and immune function
T/F: phosphorus helps to form bones and teeth
true
how many cups of skim milk are needed to meet the calcium requirement for a 25 y/o woman? (325 mg/cup)
A. 1
B. 2
C. 3
D. 4
E. 5
F. 6
C. 3
why is protein important to bone formation
creates a strong matrix and collagen
examples of non-fortified calcium based foods
dairy, canned fish, kale, collards, broccoli
examples of fortified calcium based foods
orange juice, soy drinks, milk, vit D supplements
__% of women die within a year of hip fracture
28%
what does calcium actually form in bones?
hydroxyapatite (bone mineral)
why is vitamin D important to bone structure?
preserves calcium in the skeleton
__% of men die within a year of hip fracture
37%
is calcium absorption inversely proportional?
YES (if you have good Ca status you will absorb less from food, but if youre low on Ca you'll absorb more)
what are the calcium DRIs for adolecents, adults younger than 50 and adults older than 50?
adolescents: 1300mg/d
<50: 1000 mg/d
>51: 1200 mg/d
UL: 2500mg/d
teeth are formed by ___?
hydroxyapatite on collagen matrix to create dentin
What does dentin do?
gives strength to teeth
T/F osteoporotic hip fractures consume much less hospital bed days than stroke, diabetes, or heart attack
false
What does fluoride do for teeth?
it hardens and stabilizes the crystals of teeth and makes enamel resistant to decay
T/F osteoporosis is more common than heart attack, stroke, and breast cancer combined
True
parathyroid hormone and its functions work to achieve normal:
blood calcium
T/F prevention of osteoporosis is the primary function of calcium
true
Why are bones important for calcium?
they serve as a bank that can release calcium into fluids as needed
T/F there is not a constant turnover in bone formation and bone resorption
false
Where is calcium stored
99% in the bones and teeth
what can a deficiency in iron lead to?
anemia and profound fatigue
babies are born with enough iron for ___ months
6
what are the main causes of iron-deficient anemia?
1. physiological state (pregnancy or being a child)
2. blood loss
3. poor intake
4. poor absorption
GERD stands for:
gastroesophageal reflux disease
GI stands for:
gastrointestinal
PPI stands for
proton pump inhibitor
what are some mental symptoms of anemia?
clumsiness, hyperactivity, irritability, learning disorders or lowered IQ, lack of appetite
what is an overload of iron called?
Hemochromatosis
what can hemochromatosis cause?
liver disease, premature death