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Theodosius Dobzhansky
Nothing makes sense except in the light of evolution. It’s really satisfying.
Biological evolution
The study of the processes by which life evolves and the pattern these processes have generated over the past 5 billion years
Cetaceans
Whales, dolphins, fishlike bodies, use relatively small amounts of energy to shoot through water. Generate thrust from tail moving side to side like sharks. Embryos develop in the uterus, forming placentas, and have tiny bones in flesh where hip would be on land.
Homology
Structural characters that are shared because they are inherited from a common ancestor
Baleen
Swim around and catch fish. Get huge amounts inside, like entire schools. One giant mouthful, water squirts back out through combs, leaving just the krill.
Dorudon
In teeth, is more similar to living mammals than to living odontocetes. Sees the first reduction in hindlimbs.I
Involucrum
Part of the ear in modern dolphin and pakicetus
Pakicetus
Split from dolphins. Fossils found where dolphins reside today.
18O/16O ratio
Higher in saltwater and teeth of marine animals. Shows how the switch from freshwater to seawater.
Whale’s synapomorphies
Mammary glands, three middle ear bones, and hair in developing embryos
Convergent evolution
Similarities with/between whales and fish. Attained similar traits seperately, homoplasy
Asragalus
In our ankle between the tibia and fibula. Shows common ancestry between hippos and dolphins/whales
Phylogeny
Branching patterns of evolution, synthesize evidence of a complex evolutionary history
Morphological
Form and structure of organisms
Indohyus and pakicetus
Had dense bones found in hippos. Able to stay underwater. They likely swam like otters, kicking large feet that they dragged on land. (later became obsolete, even costly.)
Cetacean brains
Biggest brain proportional to body (besides human). Earliest whales had relatively small brains. Only after water did they change drastically, as they started living in large social groups, forming alliances.
Mysticetes
Trapped small animals with their baleen
Odontocetes
Swam after fishes and larger prey, echolocation
SARS-Cov-2
50-140 nm diameter and 1000x smaller than width of hair. 26 protein coding genes.
Influenza virus
Membrane and proteins shell encasing strands of RNA. Invades host cell. Hemagglutinins bind to receptors of epithelial cells in host respiratory tract. Triggers cell to open and then move inside the virus and mass produce copies of themselves.
SARS-Cov-2 lifecycle
Spike bind to ACE-2 receptor, allows for certain things to pass, fool to gain entry, opens and excretes RNA genome. Can’t replicate so it uses ribosomes and mechanisms to copy all its genes. Creates spike proteins and is ejected.
Viral reassortment
Viruses swap genes, undergo gene shuffling (2 viruses) and become packaged into protein shells. Surface proteins are distinctly different, and humans lose immunity to it. Added urgency to detecting new flu strains
H7N9
Spread from mostly bird to human, rarely from human to human. Quite deadly. Most common antivirals weren’t doing anything.
Humans and chimpanzees
Share common ancestry. We’ve existed for like 5-7 million years, but in evolutionary terms that is considered pretty recent. That amount of divergence and we’re still 99% identical to what they are.
Macroevolution
Evolution across millions of years
Microevolution
Allele frequencies change across generations
Plato
Typological thinking. Every organism is an example of a perfect essence or type, created by God. Believed that types were unchanging.
Aristotle
Ordered organisms into linear great chain of being (or scale of nature)
The great chain of being
Species were put on a scale of lowest to highest forms and were fixed types. Plants were the lowest form of life, humans listed as higher due to ability to reason, and it was seen as God’s creation of it. Increasing size and complexity.
Linnaean classification
Discovered/introduced taxa and taxonomy. Assigned every species to a particular genus, family or order based on traits it shared. There was a belief of hybridization coming after the bible. Nested hierarchy. Gets further out and more and more inclusive.
Nicholas Steno
Dutch anatomist who dealt with things like fossil records. After sharks died, teeth were transformed to snow. Sedimentation over mountains were things originally on the ocean floor.
Stratigraphy
Studying the layers of the earth
Natural theology
Building on classic work and anatomical research in ancient Greece. Studied organs and functions. Compared old hearts of humans, snakes and fish to what had been drawn up in ancient Greece to current hearts.
Mechanical function
Seen as evidence of God’s divine creation. Complex organs were noted and later the powerful explanation of Darwin emerged through evolution by natural selection.
Buffon
Thought the world form was due to laws of physics, was only 70 000 years old. We also saw the idea of small particles between rocks and humans being the same.
George Cuvier
Compared elephants from Africa and India, and the idea of extinction. Fossils resemble modern species, and many were extinct. Mapped out the geology of other parts of the world, discovering that formations of rock exposed in one country could be found in others.
Extinction
Left blanks in the great chain of being
Mary Anning
British Naturalist, discovered many early fossils and the concept of extinction was met with considerable resistance
James Hutton
Scottish chemist and geologist. Rocks formed through imperceptibly slow changes, many of which we can see around us today. Small changes accumulated over time, and so he believed the Earth was very old.
Smith
Organized strate by oldest to youngest (fossils) and began forming a geological history. Answers for extinction in rocks below. Created the first geological map. Same layers of rock in different parts of England.
Lamarck’s theory of evolution
Life was driven from simplicity to complexity. Became popular because it was intuitive, however biologists rejected it because of how it was phenotypically related to genetic mechanisms of inheritance
Uniformitarianism
Same observable natural processes today were also responsible for events in the past. Slow process of erosion over long time, can produce massive canyons. Torrential rain, impromptu stream set up with water, can end up forming a trench.
Homology
Born based on the idea that we were all cousins and how we have very similar bone structures even with different functions. Also known as a synapomorphy.
Homologous trait
Similar due to inheritance from a common ancestors (humans begin to form gill arches)
Malthus
Believed poor people naturally selected against, which led to Darwin and Wallace’s hypotheses. A grim proposal.
Wallace
Proposed similar evolutionary ideas, collections from South America and Malay Archipelago, observations of biodiversity, common ancestry, natural selection.
Darwin and mating behaviour
Mating effects sexual selection. How fast embryos grow is affected by selection. Darwin liked heredity and genetic to select for traits, and then later on (1950s) DNA and the double helix was discovered.
Artificial selection
Humans are selective agents (breeding), and they exaggerate traits not seen in nature. Breeders can do it, so can we with nature.
Moment of catastrophe
The resources and population meet, there is not enough to sustain population and the population will crash.
Darwin postulates
Individuals within a species are available
Some variations are passed to offspring
In ever generation, more offspring are produced than can survive
Survival and reproduction is not random
Kelvin
Argued the earth was no more than 20 million years old. He was proved incorrect. He thought since the Earth was hot and had been cooling, then it must still be young, but the earth is not static. Movement of tectonic plates has changed the way the earth heats up and down.
Carbon-14
half life is 5730 years. 50% of it will become Nitrogen-14 in 5730 years.
Radioactive substances still on earth
Samarium-147, Rubidium-87, Rhenium-187, Thorium-232, Uranium-238
Countershading
Cancels out darkening shadows, makes it harder for predators to see them (smaller animals)
Computed tomography (CT scanner)
Where we resonate and produce sounds and just analyze what things sound like
Lump of coal
Remains of dead plants
Biomarkers
How plant materials are transformed, how we know the age, sediments.
Stromatolites
Large mounds built today by colonies of bacteria, grown on floors of lakes and shallow seas. Form when biofilms of microorganisms, especially cyanobacteria, trap and bind sediments to form layered accretionary structures
Enigmatic species
Edicaran fauna. Measuring a whole meter in length, looked to be like snails and clams. Only distantly related to these lineages though. Independently evolved multicellularity.
Teleosts
Most species of fish on earth came from this 350 million years ago
Synapsids
Dominant vertebrates relative to today’s mammals (sprawling creatures) came around 200 million years ago.
Hominin evolution
Key genetic and behavioural changes. 7 millions years old.
Weald
Identified stratigraphy in the rolling hills and valleys in England
Dating Earth’s layers
Geologists identified numerous rock layer around world (1800), mapped layers into chronological order. This estimated the earth to be 4.56 billion years.
Phylogeny
Evolutionary history of a lineage. Can depict populations, genes, species or higher taxonomic units.
Phylogenetic tree
Visual representation of phylogeny, can look different and depict the same thing. Don’t read along tips, look for common ancestry.
Node
Links kinship, or “same parent” of two different species, represents common ancestors of all descendent lineages
Internal nodes
Located within the phylogeny, representing ancestral populations or species that have long since disappeared.
Clade
Node and all of its descendants
Cladogram
Shows only the relationships among species
Taxa
Units of classification
Branch
Separates a group, lineages evolving over time. Connects successive speciation events or other branching events.
Monophyletic
Group of an organism and all of its descendants
Polyphyletic
Cutting the tree in two. Shared characteristics, grouping not based on common ancestor.
Paraphyletic
Includes some but not all descendants of a common ancestor
Carnivorans
Group of mammals, enlarged side teeth, shear meat off their prey
Synapomorphies
Shared derived characters, evolved in the immediate common ancestor
Outgroup
How we decide what is an ancestral and what is derived. Seeing which groups don’t fit within the clade.
Homoplasy
Similarities of independent evolution of same trait in two or more lineages
Evolutionary reversal
Derived states return back to their ancestral state on some of the branches
Parsimony
Simplest explanation for set of data is chosen as the hypothesis (not always correct explanation, but can be true).
Consensus trees
The computer selected trees based on all information
Polytomy
Comb shaped set of branches, used to represent unresolved relationships in the tree (3 split)
Nested hierarchy
Further you go back, the more inclusive you get. Katy Perry Comes Over For Good Soup.
Homologous traits
Lobe fins and tetrapods are linked by these, and most interesting in the limbs
Lobe-fins
They (as opposed to ray fin) have a chain of sturdy bones anchoring it. There was a bunch of bony projections and that was how they swam. We still have it, but the extension of several different bones as well.
Coelacanth
Discovered in 1938, was important because of how they move their fins like mammals move their limbs
Tiktaalik
Discovered in 2004, was part fish part tetrapod, like a fish with feet and fins far more elongated than Coelacanth. Scales, gill, flat head, unusual fin (walking).
Zhenyuanlong
Vaned feathers, projections off the quill form a code. All the feathers stick together and create the strength of flight. Strong but weigh very lightly.
Archaeornithura
Birds don’t have bony tails, they had a fanned tail like modern birds
Characters
Identifiable heritable traits
Character state
Condition of the character
Ancestral characters
What character was in pas ancestors (primitive)
Derived characters
What character is more advances and does not come from past ancestors
HGMA2
Carrying two copies increases height by 1 cm and the researchers have since discovered 800 loci that influence height
Gene
DNA, unit of inheritance, codes specific proteins
Proteins
Makes up most the cell, dry weight. Structure and chemical reactions in the cell. Some carry information and molecules (hemoglobin w/ oxygen). They are all made up of the same 20 amino acids.
Messenger RNA
Transcript copy of gene, encodes specific polypeptide
Ribosomal RNA
Primary component of ribosome, catalytic activity
Transfer RNA
Carries amino acid to ribosome for translation