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Signalment
Sex, Species, Breed, Production Status, Age
Presenting complaint
Reason why we are seeing that animal
History
Background info
History Examples
intact/fixed
pre-existing condition
behavioral issues
lifestyle
medications
past medical history
Physical Examination: Vital signs
Heart rate
Temperature
CRT
Respiration
Mucus Membranes
Blood Pressure
Body weight
Heart Rate Measured
Bpm - listen for 15 sec then mult. by 4 = 60 sec
What is CRT
Capillary refill time : gums, vulva, prepuce <2sec
What is respiration
breaths per minute
What are we looking for in the mucus membranes
Color and moisture (conjunctiva)
Conjunctiva
Thin membrane that lines the inside of the eyelid
More parts of the physical Examination consist of what
skin/haircoat
gut sounds
Rumen contractions
musculoskeletal system
discharge
neurologic exams
distention/abdominal contour
behavior and visual assessment
dental/oral
repro.
urinary tract
What are we looking fro in the Musculoskeletal System?
Lameness/sound
Muscle tremors
Muscle Fasciculations
Muscle Atrophy/ joints —> ROM effusion
Borborygmi
Sounds of the gut
epiphora
excess tears/watery eyes
How and where do we check for hydration status
Skin turgor/skin pinch test
between shoulder blades -small animals
Neck/point of shoulder-equine
Upper eyelid-rumminants
Other indicators of Hydration
Mucus membrane moisture
urine color and volume
moisture on the nose
PCV/TP (packed cell vol. / total protein)
eye position (sunken eyes)
What is the First statement about an animal’s status?
Signalment
What else are we looking for in the heart besides the bpm?
pulse and auscults (murmurs , arrhythmias)
What is the % hydration status , when animals begin to show signs of dehydration
equal to or >5%
Where do you check for hydration status
Small animals: between the shoulders
Equine: Neck/point of shoulder
Ruminants: upper eyelids
What are some other indications of dehdration
mucus membrane
urine color/volume
moisture on nose
PCV/TP: packed cell volume
sunken eyes
Where is the Saphenous Vein for Dogs and Cats
Dogs: Lateral (outside) hind limb
Cats” Medial (inner) hind limb
Where is the Cephalic vein
On the forelimb
OU
both eyes
OD
Right eye
OS
left eye
AU
Both ears
AD
right ear
AS
left ear
Blepharospasm
Squinting
Melanosis
Pigmentation
Monocytopenia
low monocyte coutn
What elements comprise the blood
Cells + plasma
What is in Plasma
proteins
electrolytes
gases
enzymes
hormones
ions
Hematopoiesis
Process by which blood cells are formed in the bdoy
What is in a hematocrit tube
Plasma, Buffy coat, packed red blood cells, wax plug
Hemogram
measures RBC, WBC,Thrombocytes
determines total protein
Fibrinogen
an inflammatory protein
Erythrocytes - RBC
Biconcave disks
made in the bone marrow
What happens to damaged RBC
they are broken down and removed from the bloodstream
happens in the bone marrow, liver, and spleen
What do Erythrocytes do?
They deliver oxygen- tiny bomb of oxygen
and haul off waste CO2
part of capillary blood flow
What is the FAMCHA score
scores severity of Anemia on scale of 1-5
What are the 5 types of Leukocytes / WBC
Granulocytes
Neutrophils
eosinophils
basophils
Agranulocytes
Monocytes
macrophages
lymphocytes
What is it called when WBC counts are higher
Leukocytosis
What is it called when WBC counts are lower
Leukopenia
Neutrophils
A granulocytes
lobulated+highly segmented
First defenders of immune system
highly motile
equipped with an armory
also known as Polymorphonuclear cells
they moved based on chemical gradients: Chemotaxis
Neutrophiles
Granulocyte
Bands=immature neutrophils
seen when body experiences overwhelming inflammatory signals and bone marrow cant keep up —> infection
Left shift
How do Neutrophils kill microbes
Oxidative/Respiratory burst
cytoplasmic granules fuse with the phagosome and discharge lethal components into direct contact with offending microbe
How do Neutrophils circulate
only briefly- and may remain in circulation only for hours before migrating into tissues
How do cells leave the vascular space
Diapedesis
Do neutrophil granules destroy hot tissue
Yes
What is an accumulation of Neutrophils
suppurative exudate/purulent discharge
pus
Eosinophils
granulocyte
Bilobed nucleus
cytoplasmic granules-red/pink
Granule contents are active chemicals
they increase in response to allergic conditions and parasites
How do Eosinophils kill
they kill by exocytosing granules, the granule contents are introduced into the tissue
What does high number of eosinophils mean
seen with parasitism and allergy
plus some neoplastic diseases
eosinophils are seen with
worms
Parelaphostrongylus tenuis
meningeal worm
causes brain and spinal cord lesions
llamas, moose, and reindeer
Eosinophilic granuloma complex in cats
caused by hypersensitivity reactions to drugs, food allergies, fleas,and genetic predisposition
Basophils
Blue
numbers increase in response to SOME allergic reactions
numbers ten to be low in normal animals
Basophils and mast cells
Circulation=basophils
Tissues=mast cells
both sited at portals of entry to contian invaders
they dscharge granules that contian histamine and heparin
both important in allergic reacitons
Histamine
dilates blood vessels
Heparin
Prevents blood clotting
Are monocytes phagocytes
yes
What do Monocytes do
secrete Cytokines
amp up immune response
Cytokines
lead to feelings of illness, fever, arthralgia, myalgia, chills
immune responses
amplify a local response into a body wide systemic response
What do monocytes turn into when they enter tissues
Macrophages
Where are Macrophages located
Lungs
Liver
Peritoneal cavity
Synovium
connective tissues
macrophages in the lungs
alveolar and interstitial macrophages
Macrophages in the liver
line liver sinusoids-Kupffer cells
T/F Monocytes are responsible for destryoing senescent RBS
True
Are lymphocytes Granulocytes
NO
What are Lymphocytes apart of in terms of the immune system
ADAPTIVE IMMUNITY
What must Lymphocytes do, unlike neutrophils
recognize antigens
cell-mediated responses
antibody-mediated responses
What antigen classes do Lymphocytes attack
T cells
B cells
Natural killer cells
T cells
T helper cells, cytotoxic T cells, T regulatory cells
Vaccine
preparation of weakened/killed pathogen (bacteria/virus) or a portion of a pathogen’s structure that stimulates antibody production against the pathogen but is incapable of causing severe infection
Antigen
Substance that stimulates the immune system and causes antibody production
Antibody
A protection protein produced by the body in response to a disease causing organism or vaccine
Adjuvant
Immunological agent that enhances the immune response to a vaccine
Type of Vaccine: Killed/Inactive
use of killed version of antigen that causes disease
cant cause disease
provides immunity weaker than live vax
Type of Vaccine: Modified-Live/attenuated
use of weakened form of antigen that causes a disease
create strong and long-lasting immune response
can cause mild disease
Type of Vaccine: Recombinant
made by identifying key antigens, removing/splicing genes from the pathogens that code then recombine
adjuvant free—> does not enhance immune system
Type of Vaccine: Toxoid
use of toxin made by germ that causes disease
creates immunity to parts of the germ that cause disease instead of germ instead
allows immune response to be target to the toxin
Example of killed/inactive vaccine
Rabies
Example of Modified-live (MLV)/Attenuated
DAPP, DHLPP, FVRCP
Example of Recombinant vaccine
Purevax vaccines: Feline rabies, Feline leukemia
Example of Toxoid vaccine
Rattlesnake vax, Tetanus vax (large animals)
What are Core vaccines
vaccines that should be given to all animals of a particular species
What determines Core vaccines
risk of exposure
severity of disease
transmissibility
Examples of Core vaccines
K9: canine parvovirus, distemper, adenocirus (hepatitis), rbaies
Fel: herpes (rhinotracheitis), calicvirus, panleukopenia, rabies
What are Non-core vaccines
Vaccines that should be given to specific animals that have a lifestyle that puts them at risk for a particular disease
What are examples of Non-core Vaccines
K9: leptospirosis, rattlesnake, lyme, influenza, bordetella
Fel: leukemia, chlamydia, bordetella, feline infectious peritonitis (FIP)
What vaccines are Subcutaneous
Rabies, DHPP,Lepto, influenza
What vaccines are intranasal
Bordetella
What vaccines are Oral
bordetella
For SQ what vaccines are given in the left front
K9: lepto (if not given in combo with DHPP)
For SQ what vaccines are given in the Right front
K9: DHPP/DHLPP
Fel: FVRCP
For SQ what vaccines are given in the left Rear
K9: rattlesnake —→ deep SQ w/ 20G needle and alternate side for booster
Fel: Leukemia (distal to the left stifle)
For SQ what vaccines are given in the Right rear
K9/Fel: rabies RRR