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What does Cell Theory state?
All living organisms are made of cells, they are the smallest unit of life, and that cells come other cells
Prokaryotes
Single-celled organisms without a nucleus or membrane bound organelles, either bacteria or archaea; DNA floats in the nucleoid
Eukaryotes
Larger organisms with complex organelles that are often membrane-bound, and that include plants, animals, fungi, and protists; has a full nucleus
Plasma Membrane
Selectively permeable phospholipid bilayer, with proteins controlling what enters and exits
Nucleus
Control center of eukaryotic cells that directs protein synthesis and contains the DNA of the cell
Nucleoid
Region in prokaryotes where DNA is concentrated (not membrane-bound)
Nucleolus
Dense structure inside the nucleus that makes ribosomal RNA (rRNA) and assembles ribosome subunits
Cytoplasm
Entire region between the nucleus and plasma membrane, including organelles and cytosol.
Cytosol
The jelly-like fluid in which organelles float
Ribosomes
Molecular machines made of rRNA; proteins that build proteins from mRNA instructions, found free in the cytosol or on the rough ER
Cell Wall
Rigid outer layer in plants, fungi, and some prokaryotes that protects, supports, and shapes the cell; made of cellulose in plants.
Internal Membrane System
Network of membranes in eukaryotes that organizes reactions and transport (ER, Golgi, vesicles)
Flagella
Long whip-like structures used for movement
Pili
Short, hair-like projections in bacteria used for attachment or DNA exchange (conjugation)
Cytoskeleton
Dynamic protein network that provides support, shape, and movement inside cells.
Organelle
Specialized, membrane-bound compartment in eukaryotic cells with a unique function.
Mitochondria
Double-membrane organelles that generate ATP through cellular respiration; contain their own DNA and ribosomes.
Golgi Apparatus
Stack of flattened sacs that modifies, sorts, and ships proteins and lipids.
Endoplasmic Reticulum (rough)
Studded with ribosomes; site of protein synthesis and modification.
Endoplasmic Reticulum (smooth)
Lacks ribosomes; synthesizes lipids, detoxifies, stores calcium.
Lysosome
Enzyme-filled vesicles that digest macromolecules and recycle cellular components
Vacuole
Large vesicles for storage, digestion, and water balance; especially big in plant cells for turgor pressure.
Chloroplast
Double-membrane organelles with thylakoids where photosynthesis occurs; contain their own DNA.
Plastid
Plant organelles that store or synthesize compounds (chloroplasts, chromoplasts, amyloplasts)
Peroxisome
Organelles that break down fatty acids and detoxify harmful substances using peroxide
Thylakoid
Flattened sacs inside chloroplasts where the light reactions of photosynthesis occur (stacked into grana)
Glyoxysome
Specialized peroxisomes in plant seeds that convert fats into sugars for energy during germination
Microfilaments
Thin actin filaments involved in cell shape, movement, and muscle contraction
Intermediate Filaments
Rope-like fibers providing structural strength and anchoring organelles.
Microtubules
Hollow tubes of tubulin that form tracks for organelle movement, make spindle fibers, and build cilia/flagella
Surface Area - Volume Ratio
A measure that limits cell size; smaller cells have more surface area relative to volume, aiding efficient exchange
Endosymbiotic Theory
The idea that mitochondria and chloroplasts originated as prokaryotes engulfed by ancestral eukaryotic cells
Motor Protein Movement
Proteins like kinesin and dynein that “walk” along microtubules, hauling organelles/vesicles using ATP
Cell Fractionation
Lab technique that breaks cells and separates components by size/density using centrifugation
Nuclear Envelope
Double membrane with pores that surrounds the nucleus, regulating traffic of RNA and proteins; connected with the membrane of the rough ER
Integral Membrane Protein
Proteins embedded in membrane, involved in transport, signaling, or anchoring
Peripheral Membrane Protein
Proteins loosely attached to membrane surface (inside or outside), often for signaling or support.
Glycolipid
Lipid with carbohydrate chain attached; used for cell recognition, cell-to-cell communication, and cell membrane stability
Glycoprotein
Protein with carbohydrate chain attached; used for cell recognition, cell adhesion, acts as receptors*
Cell Recognition
The ability of cells to identify each other using carbohydrate “tags” on proteins/lipids
Cell Adhesion
Process of cells sticking together via proteins or carbs
Homotypic Bonding
Cells sticking via the same proteins on each cell surface.
Heterotypic Bonding
Cells sticking via different surface proteins that match like lock-and-key.
Cell Junction
Specialized structures that link cells together
Tight Junction
Seals cells together to prevent leakage (like in the intestine).
Desmosome
Anchoring junctions that hold cells together like rivets, connected to intermediate filaments
Gap Junction
Channels that connect animal cells for direct communication of ions/small molecules
Plasmodemata
Plant cell channels through cell walls that allow exchange of water and molecules
Extracellular Matrix
Network of proteins (like collagen) and carbs outside cells that provides support and regulates cell behavior
Selective Permeability
The plasma membrane’s ability to regulate what enters and leaves the cell
Diffusion
Movement of molecules from high to low concentration (no energy).
Isotonic Solution
Solute concentration equal inside and out → no net water movement.
Hypertonic Solution
Higher solute outside → water leaves cell → shrinks (plasmolysis in plants).
Hypotonic Solution
Lower solute outside → water enters cell → swells (plants = turgid; animals risk lysis)
Facilitated Diffusion
Passive transport using channel or carrier proteins
Channel Proteins
Membrane proteins forming tunnels for molecules to pass through.
Ion Channels
Proteins that allow ions to move down their concentration gradient.
Gated Channels
Ion channels that open/close in response to a stimulus (voltage, ligand, mechanical).
Membrane Potential
The voltage difference across a cell’s membrane, created by ion gradients.
Aquaporins
Channel proteins specifically for water transport.
Sodium Potassium Pump
Active transport protein that pumps 3 Na⁺ out and 2 K⁺ in, maintaining membrane potential. Requires ATP
Membrane Fluidity and Cholesterol
Phospholipids move laterally; cholesterol prevents too much rigidity (cold temps) or fluidity (hot temps).
Active Transport
Movement of molecules against their gradient, requiring energy (usually ATP).
Uniports
Transport proteins moving one molecule in one direction.
Symports
Transport proteins moving two molecules in the same direction
Antiports
Transport proteins moving two molecules in opposite directions
Phagocytosis
Cell eating; engulfing large particles into vesicles
Pinocytosis
“Cell drinking”; engulfing fluids and dissolved solutes
Receptor-mediated Endocytosis
Uptake of specific molecules using receptor proteins and clathrin-coated pits.
Receptor Proteins
Proteins that detect signals or bind specific molecules, triggering cellular responses
Clathrin Coated Pits
Specialized pits with a clathrin protein coat that form vesicles in receptor-mediated endocytosis.
Exocytosis
Vesicles fuse with the plasma membrane to release materials outside.
Membrane functions (other)
Communication – Receptors receive signals.
Compartmentalization – Separates reactions into organelles.
Transport – Regulates exchange of molecules.
Recognition/Identity – Glycoproteins & glycolipids serve as ID tags.
Anchoring – Connects to cytoskeleton & ECM.