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What are the early stages in the development of the testis?
Suppression of paramesonephric duct
Formation of primary sex cords
Primary sex cords condense and extend into the medulla of the gonad
Which forms prominent sex cords
What happens in the intermediate stage of testis development?
Testis cords anatomomose with the rete testis
What occurs during testicular differentiation?
Formation of seminiferous tubules, parenchyma and interstitial tissue
Development of External Genitalia
What hormone is responsible
What does the genital tubercle develop into under DHT influence
What does the cloacal fold divide into
What structure forms scrotum
What does the urogenital fold fuse into?
What hormone is responsible: AMH (suppresses female duct development)
Therefore these structures change into:
Genital tubercle: Elongates to form penis
Cloacal fold divide into: Urogenital fold and anal fold
Lateral scrotal swellings form: Scrotum
Urogenital fold fuse into: Penile urethra
Testicular Decent
What is the transabdominal phase of testicular descent
What is the gubernaculum
What happens when the gubernaculum enlarges
What directs testicular migration
What happens to gubernaculum after descent
What is the transabdominal phase of testicular descent: When the testis moves near the mesonephros and posterior to the abdominal wall
What is the gubernaculum: Ligament that guides the descent of testis
What happens when the gubernaculum enlarges: It anchors to the scrotum and pulls testis through the inguinal ring
What directs testicular migration: Testosterone and genitofermoral nerve secretion
What happens to gubernaculum after descent: It shortens, regresses and its remnant persists in scrotum