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Biology
Study of life and living organisms.
Organisms
Are made up of chemical elements and their compounds.
Chemical Elements (List)
Carbon
Organic compounds (Characteristic 1)
Contain carbon.
Organic compounds (Characteristic 2)
Are complex.
Organic compounds (Characteristic 3)
Are produced / associated with living things.
Four major types of organic compounds
Carbohydrates, lipids, proteins and nucleic acids
Macromolecules
Very large organic molecules (macro – large).
Subunits/Monomers
Smaller molecules that make up macromolecules.
Macromolecules (Role 1)
Have vital roles within cells.
Macromolecules (Role 2)
Are used as energy reserves.
Important Macromolecules (Example)
Polysaccharides and lipids.
Carbohydrates (saccharides)
Molecules made of carbon
Monosaccharides and Disaccharides
Relatively small carbohydrate molecules.
Polysaccharides
Very large carbohydrate molecules.
Glucose (Primary Role)
Source of energy.
Starch and Glycogen (Primary Role)
Store of energy.
Cellulose (Primary Role)
Structural component.
Monosaccharides (Simple sugars)
Single sugar units.
Monosaccharides/Disaccharides (Properties)
Have a sweet taste and dissolve in water.
Disaccharides (Simple sugars)
Two monosaccharide units joined together.
Polysaccharides (Complex sugars)
Large molecules composed of 100s or 1000s of simple sugar units (monosaccharides) joined together.
Starch (Composition
Role
Glycogen (Composition
Role
Cellulose (Composition
Role
Chitin (Composition
Role
Starch (Formation)
Excess glucose molecules joined together during photosynthesis.
Starch (Storage Location)
Stored in chloroplasts and the cytoplasm of plants.
Starch (Solubility/Osmosis)
Not soluble in water
Starch (Breakdown)
Broken back down to glucose (hydrolysed) when needed.
Glycogen (Formation)
Excess glucose molecules joined together.
Glycogen (Storage Location)
Mainly in muscle and liver cells
Glycogen (Breakdown)
Converted back (hydrolysed) to glucose when needed.
Cellulose (Function)
Major component of plant cell walls
Cellulose (Physical properties)
Tough
Cellulose (Permeability)
Permeable to water.
Cellulose (Dietary role)
Forms roughage/fibre
Chitin (Specific Location 1)
Forms the exoskeleton structure of insects
Chitin (Specific Location 2)
Forms the cell wall in fungi.
Chitin (Support Role)
Acts as support.
Lipids (Role List)
Energy storage
Energy storage lipids (Triglycerides)
Organic molecules composed of fatty acid chains linked to a glycerol backbone.
Fat (Definition/Storage)
Solid at room temperature
Fat conversion
When food intake is reduced
Oils (Definition/Location)
Liquid at room temperature
Phospholipids (Composition)
Contain a phosphate group and 2 fatty acid chains attached to a glycerol backbone.
Phospholipids (Structural role)
Major component of cell membranes
Phospholipid arrangement in water
Phosphate groups towards water; fatty acid chains towards each other.
Steroids (Examples)
Many animal hormones such as oestrogen and testosterone.
Waxes (Role)
Protective layers in animals and plants.
Cholesterol (Role 1)
Component of animal cell membranes.
Cholesterol (Role 2)
Required for vitamin D synthesis.
Cell Theory (Point 1)
All organisms are made up of one or more cells.
Cell Theory (Point 2)
The cell is the simplest unit of life – the place where all chemical reactions occur.
Cell Theory (Point 3)
All cells are produced from pre-existing cells
Robert Hooke (1665)
Examined cork and used the term ‘cells’.
Antonie van Leeuwenhoek (1675)
Saw tiny animalcules (bacteria).
Mathias Schleiden (1837)
German Botanist who stated all plants are made of cells.
Theodor Schwann (1839)
German physiologist who stated animals were comprised of cells and that the cell is the basic structure of all organisms.
Rudolf Virchow (1855)
German doctor who stated every cell comes from pre-existing cells.
Light Microscopes
Pass a beam of light though a thin section and magnify up to 1500x.
Light Microscope Focusing
Light is focused through lenses
Electron microscopes
Pass a beam of electrons through a vacuum then a thin section
TEM
Transmission Electron Microscope
SEM
Scanning Electron Microscope
Micrometre (μm)
Unit used to measure cells; 1μm is 10−6m
Typical cell size range
10μm – 30μm.
Prokaryote size
1μm.
Eukaryote size
10μm – 100μm.
Nanometre (nm)
Unit used to measure structures within the cell; 1000nm=1μm.
Two basic types of cell organization
Prokaryote and Eukaryote.
Prokaryote example
Bacteria.
Eukaryote examples
Animals
Prokaryote nucleus structure
No separate nucleus.
Eukaryote nucleus structure
Membrane bound nucleus.
Prokaryotic cells (Characteristics)
Small
Prokaryotic DNA
Single
Prokaryotic organelles
No membrane bound organelles.
Prokaryotic ribosomes
Ribosomes found in the cytoplasm
Eukaryotic cells (Characteristics)
Are larger and more complex.
Eukaryotic DNA
Several linear chromosomes
Eukaryotic organelles
Have membrane-bound organelles.
Cell membrane (Composition)
Lipoprotein structure found in all living cells.
Cell membrane (Function)
Semi-permeable barrier that controls entry and exit of materials (nutrients and wastes).
Cell membrane structure (Layers)
Consists of two layers of phospholipid molecules (bi-layer) embedded with proteins.
Fluid Mosaic Model (Developers/Year)
Developed by Singer and Nicolson in 1972.
"Fluid" in Fluid Mosaic Model
The ability of proteins and lipids to move sideways within the structure.
"Mosaic" in Fluid Mosaic Model
The variety of protein molecules embedded/attached to the phospholipid bi-layer.
Proteins (Cell membrane role)
Determine the function of the cell membrane.
Phospholipid arrangement in bilayer
Hydrophobic tails point towards each other; hydrophilic heads are on the surface of the membrane.
Channel & carrier proteins
Span the membrane (pass all the way through) and allow substances to pass through.
Passive transport (Channel/Carrier)
Movement such as diffusion that requires no energy.
Active transport (Channel/Carrier)
Movement that requires energy.
Receptor type proteins (Function)
Involved in cellular communication and recognition of antigens and hormones.
Proteins on underside of membrane
Held in place by the cytoskeleton.
Cytoskeleton (Definition)
An internal framework of microtubules
Cytoskeleton attachment
Attached to the cell membrane.
Cytoskeleton Function 1
Gives cells shape and enables them to change shape.
Cytoskeleton Function 2
Anchors and moves organelles in and through cytoplasm.
Cytoskeleton Function 3
Involved in cell movement.