Table 26.7 Reactive Morphologic Changes in Neutrophil
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6 Terms
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Toxic granulation appearance
Dark, blue black cytoplasmic granules
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Toxic granulation is associated with
Inflammation, infection, G-CSF
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Dohle bodies appearance
Intracytoplasmic pale blue round or elongated bodies between 1 and 5 micrometer in diameter, usually adjacent to cellular membrane
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Dohle bodies are associated with
Infection, G-CSF, pregnancy, burns
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Cytoplasmic vacuoles
Small to large circular clear areas in cytoplasm, rarely may contain organism.C
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Cytoplasmic vacuoles are associated with
Bacterial infections, autophagocytosis secondary to drug ingestion, acute alcoholism, or excess storage of sample before making blood film.
Note 
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