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Cell Theory
all living organisms are composed of cells, cells are the smallest unit of life, and new cells come only from pre-existing cells
Origin of cells
life originated from inorganic molecules in the primordial ocean and inorganic molecules could be synthesized from inorganic components
Discovery of cells
In 1665, Robert Hooke observed a cork under a microscope and seeing its honeycomb like structure
Types of microscopes
Compound light, Stereo-dissecting, Scanning electron, Transmission electron
Compound Light Microscope Use
uses visible light, useful magnification up to 1000x
Stereo-Dissecting Microscope Use
for viewing larger objects utilizing a greater working distance
Scanning Electron Microscope (SEM) Use
for viewing specimen surfaces, uses beam of electrons, 30,000-50,000 X useful magnification
Transmission Electron Microscope (TEM) Use
for viewing ultrathin sections, uses beams of electrons, 100,000-250,000X useful magnification
Characteristics of Prokaryotes
lack of membrane, kernel-like appearance, simple structure
Characteristics of Eukaryotes
possess a true nucleus, exhibits extensive compartmentalization, unique structure
Organelles unique to animal cells
nucleolus, nucleus, nuclear pore, nuclear envelope, chromatin, centrosome, ribosome, lysosome, plasma membrane, rough & smooth ER, mitochondrion, cytoskeleton, peroxisome, golgi apparatus, cytosol
Organelles unique to plant cells
nucleolus, nucleus, nuclear pore, nuclear envelope, chromatin, central vacuole, ribosome, cell wall, plasma membrane, rough & smooth ER, mitochondrion, cytoskeleton, chloroplast, peroxisome, golgi apparatus, cytosol
Organelles in bacteria cell
nucleoid, plasma membrane, cell wall, glycocalyx, flagella, pili, cytoplasm, ribosomes
Functions of nucleoid
site where the DNA is found
Function of plasma membrane (bacteria)
encloses the cytoplasm
Functions of cell wall (bacteria)
provides support and protection
Functions of glycocalyx
Outer gelatinous covering
Functions of flagella
allows certain bacteria to swim
Functions of pili
allows bacteria to attach to surfaces and to each other
Functions of cytoplasm (bacteria)
site of metabolism
Function of ribosomes
synthesizes polypeptides
Functions of nucleus
area where most of the genetic material is organized and expressed
Functions of nuclear envelope
double membrane that encloses the nucleus
Function of nuclear pore
passageway for molecules into and out of the nucleus
Functions of chromatin
a complex of protein and DNA
Function of lysosome
degrade macromolecules
Function of plasma membrane (eukaryotic)
controls movement of substances into and out of the cell
Function of cytosol
pathways for metabolism
Function of peroxisome
breaks down hydrogen peroxide and other harmful molecules
Functions of cytoskeleton (eukaryotic)
provide shape and aid in movement with protein filaments
Function of mitochondrion
ATP synthesis
Functions of Rough ER
sorting and secretion of proteins
Function of Smooth ER
lipid synthesis and detoxification
Function of centrosome
growth of microtubules and staying of centrioles
Function of nucleolus
submit assembly of ribosome
Function of chloroplast
photosynthesis
Function of central vacuole
provides storage, regulation of cell volume
Function of cell wall (plants)
provides cell support
Organelles with double membrane
nucleus, mitochondria, chloroplasts
Plasma membrane properties
semi-permeable
Tay Sachs
a vital hydrolytic enzyme, found in the lysosomes, that breaks down sphingolipids
Flagellum composition
generates bends alternatively in each direction that begin at the head and more toward the tip of the flagellum
Cilium composition
same internal structure and function as flagella, but shorter and more numerous
Centriole composition
in centrosomes, an obvious pair of structures arranged perpendicularly to each other
Type of filaments in cytoskeleton
microfilaments, microtubules, intermediate filaments
Actin
a protein found in microfilaments, helps in muscular contraction
Myosin
a motor protein
Autophagy
a process where cellular material, becomes enclosed in a double membrane
Endocytosis
a process where the digestion of substances are taken up from the outside cell
Exocytosis
materials inside the cell is packaged into the vesicles and then excreted
Pinocytosis
invloves the formation of membrane vesicles from the plasma membrane
Phagocytosis
process of protits engulfing food into large food vacuoles
Endosymbiosis
a symbiotic relationship in which the smaller species lives inside the larger species
Endomembrane System
large network of membranes that enclose the nucleus
Cell evolution (mitochondria)
evolved from aerobic alpha-proteobacteria that were engulfed by an archael host cell
Cell evolution (chloroplast)
evolved from cynabobacterium that was engulfed by a non-photosynthetic eukaryotic cell
Function of extracellular matrix
provides support and helps to organize cells
Composition of extracellular matrix
water, polysaccharides, and proteins
Functions of proteoglycans
providing resistance to compression
Cellulose (polysaccharide)
a polysaccharide made of repeating molecules of glucose attached end to end
Chitin
a nitrogen-containing polysaccharide, forms the hard protective outer covering
Collagen
provides high tensile strength to many parts of an animal's body
Cellulose
the main macromolecule of the plant cell wall
Wrinkling and collagen
the amount of collagen that is synthesized in the skin significantly decreases
Functions of plant cell walls
provide rigidity for mechanical support and maintain the cell shape and growth
Components of plant cell walls
primary cell wall (thin) and secondary cell wall (thick)
Types of anchoring junctions
adherens junctions, desmosomes, hemidesmosomes, focal adhesions
Adherens Junctions
are organized into bands around cells, binds to actin filaments in the cytosol
Desmosomes
spotlike points of intercellular contact that rivet cells together, connected by intermediate filaments
Hemidesmosomes
connect cells to the extracellular matrix, they interact with intermediate filaments
Focal Adhesion
connect cells to extracellular matrix, in the cytosol, they bind to actin filaments
Transport between cells of ions
ion transport pathways across the root endodermis
Selective permeability
allows the passage of certain ions or molecules but not others
Membrane proteins
integral, peripheral, lipid-anchored
Function of Integral membrane
transports, adhesion to other cells, and signal transduction
Function of Peripheral membrane
carry signals either to a cell or inside a cell
Function of Lipid-Anchored proteins
cell signaling and regulating protein localization & interaction
Characteristics of passive diffusion
requires no energy and moves substances concentration down
Osmosis
the movement of water across a membrane to balance solute concentrations
Osmotic pressure
pressure needed to balance the concentration difference that drives water movement
Hypertonic
concentration of solutes outside a cell is higher
Hypotonic
outside of the cell have a lower concentration of solutes than the inside
Isotonic
when the concentrations of solutes on both sides of the plasma membrane are equal
Aquaporins
a transport protein in the form of a channel that allows the rapid diffusion of water across the cell membrane
Concentration gradient
situation where the concentration of a solute is higher on one side of a membrane than on the other
Facilitated diffusion
a transport protein provides a passageway for substance to cross a membrane from high to low concentrations
Active transports
moves a substance from an area of low concentration to one high concentration
Similarities of passive, facilitated, and active transport
all move substances across cell membranes and rely on its selective permeability
Differences of passive, facilitated, and active transport
passive uses no energy for transportation, active moves substances against the gradient
ATP
a molecule that is a common energy source for all cells
Sodium potassium pump
a trans-membrane protein that helps establish the resting membrane potential of cells
Ion gradients
electrical and chemical (electrochemical)
Endocytosis
plasma membrane folds inward to form a vesicle that brings substances or particles into the cell
Exocytosis
material inside the cell is packaged into vesicles and the excreted into the extracellular environment
Receptor mediated endocytosis
a receptor in the plasma membrane specific for a given cargo
LDL (low density lipoprotein)
a type of cholesterol that carries cholesterol from the liver to the arteries
HDL (high density lipoprotein)
a type of cholesterol that carries cholesterol from the arteries back to the liver for removal
first law of thermodynamics
Energy cannot be created or destroyed
Second law of thermodynamics
every energy transfer or transformation increases the entropy of the universe.
Entropy
measure of disorder