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Why Drug Delivery Systems (DDS)?
Controlled release
Better effect
Fewer side effects
CONVENTIONAL vs DDS
Conventional | DDS |
Peaks & troughs ❌ | Constant level ✅ |
MUST-KNOW SYSTEMS - overview
OSMOTIC PUMP
MATRIX vs RESERVOIR (AGAIN)
AMORPHOUS vs CRYSTALLINE
NANOPARTICLES
OSMOTIC PUMP
Water enters → pressure → drug pushed out
Example: OROS
AMORPHOUS vs CRYSTALLINE
Type | Key Idea |
Crystalline | Stable, low solubility |
Amorphous | unstable, High solubility |
NANOPARTICLES
Very small particles
↑ solubility
↑ bioavailability
Tumor targeting