GH Lecture 3 - Mendelian Genetics 1

This is a trait whose allele is found on any autosome, rather than on a sex chromosome. Recessive traits only manifest if an individual has 2 copies of the recessive allele.

What is an autosomal recessive trait?

This is a trait whose gene is found on the X chromosome only. A Y-chromosome does not posses an allele for this trait

What is an X-linked trait?

Both alleles are expressed

What is codominance?

This is a blending of alleles in a heterozygote

What is incomplete dominance?

No, these are exceptions

Are co-dominance and incomplete dominance in accordance with Mendelian laws of inheritance

P1

What is the abbreviation of the parental generation?

F1

What is the abbreviation of the hybrid first filial/first cross generation?

F2

What is the abbreviation for the generation that results from interbreeding of the F1 generation

1(AA):2(Aa):1(aa)

What is the expected gneotypic ratio in the F2 generation?

The Phenotypre (Not the gene)

What does "dominant" and "recessive" actually refer to?

Individuals can have 3 outcomes: No Thalassemia (2 normal alleles - homozygote); Mild thalassemia (heterozygote), Severe thalassemia (Homozygote for thalassemia)

Explain incomplete dominance with the example of Thalassemia

An position on the genome that a gene occupies, such as on a chromosome or in relation to other genes

What is a locus?