Functional group transformations

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24 Terms

1
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Alcohols → Aldehydes

Oxidation in the presence of K₂Cr₂O₇ or KMnO₄

2
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Aldehydes → Carboxylic acids

Oxidation in the presence of K₂Cr₂O₇ or KMnO₄

3
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Alcohols → Carboxylic acids

Oxidation in the presence of K₂Cr₂O₇ or KMnO₄

4
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Carboxylic acids → Aldehydes

Reduction in the presence of LiAlH₄

5
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Aldehydes → Alcohols

Reduction in the presence of LiAlH₄

6
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Carboxylic acids → Alcohols

Reduction in the presence of LiAlH₄

7
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Alcohols → Ketones

Oxidation in the presence of K₂Cr₂O₇ or KMnO₄

8
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Ketones → Alcohols

Reduction in the presence of LiAlH₄

9
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Carboxylic acids → Salts

Neutralisation with a base or displacement with a metal

10
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Carboxylic acids → Alkylammonium salts

Condensation reaction when reacted with amines

11
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Alkylammonium salts → Amides

Heat

12
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Amides → Carboxylic acids

Hydrolysis in the presence of water or acid

13
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Alcohols → Esters

Condensation reaction in the presence of carboxylic acids with a concentrated H₂SO₄ of concentrated H₃PO₄ catalyst or acid chlorides with no catalyst

14
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Alcohols → Alkenes

Dehydration reaction in the presence of concentrated H₂SO₄, concentrated H₃PO₄ or Al₂O₃

15
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Alkenes → Alcohols

Hydration reaction in the presence of H₂SO₄ catalyst

16
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Alkenes → Alkanes

Hydrogenation reaction in the presence of a nickel or platinum catalyst

17
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Alkenes → Dihaloalkanes

Halogenation reaction in the presence of a halogen

18
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Alkenes → Monohaloalkanes

Hydrohalogenation reaction in the presence of a hydrogen halide

19
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Monohaloalkanes → Alkenes

Elimination reaction in the presence of ethanolic KOH or NaOH

20
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Monohaloalkanes → Ethers

Nucleophilic substitution reaction with an alkoxide

21
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Alcohols → Alkoxides

Displacement reaction with a group 1 metal

22
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Monohaloalkanes → Nitriles

Nucleophilic substitution reaction with ethanolic KCN or NaCN

23
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Monohaloalkanes → Alcohols

Nucleophilic substitution reaction with aqueous KOH or NaOH

24
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Nitriles → Carboxylic acids

Hydrolysis reaction involving water