Cyanide Poisoning

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Based on Cyanide poisoning case study in class

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1
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What is the chemical formula of cyanide?

-C≡N

2
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How does cyanide cause cyanide poisoning?

CN- binds to Fe3+ in CcOx and blocks O2 from binding to the Fe3+, this prevents O2 from being reduced to H2O and as a result the ETC stops and the H+ gradient dissipates resulting in no ATP production, and cells die as a result

3
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What are the symptoms of acute cyanide poisoning?

shortness of breath, hyperventilation

leads to seizure, then coma, then death

4
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How long does it take for someone to die after CN- poisoning?

hours to days

5
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What is the treatment for CN- poisoning?

hydroxocobalamin and Na thiosulfate