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Stimulus
Any change in the environment of sufficient intensity to excite a nerve.
RMP
Resting Membrane Potential; the potential difference across the membrane at rest (usually -70mV).
Causes of RMP
"Selective permeability to K+ (leakage)
Depolarization
The first stage of the action potential spike; caused by rapid Na+ influx (entry).
Repolarization
The return to resting potential; caused by K+ efflux (exit).
Spike Potential
"The rapid
Ionic Basis of AP
The movement of Na+ into the cell and K+ out of the cell via voltage-gated channels.
Hyperpolarization
A stage where the membrane potential becomes more negative than the RMP due to slow K+ channel closure.