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TSH
thyroid stimulating hormone
What does TSH do?
increases TH levels (T3/T4)
What are the affects of TSH?
normal development, maintain metabolism
ACTH
adrenocorticotropic hormone
What does ACTH do?
stimulates adrenal cortex to increase glucocorticoid hormone secretion (cortisol)
When do ACTH levels peak?
morning
What are the triggers of ACTH?
fever, hypoglycemia, STRESS
What is POMC?
proopiomelanocrtin
What does POMC do?
precursor protein, cleaves into 4 other active molecules
What is POMC a source of?
ACTH, lipotropins, endorphins, analgesia, MSH
FSH
follicle stimulating hormone
How does FSH work in females?
follicle maturaiton, estrogen secretion in ovary
How does FSH work in males?
produce sperm in testes
LH
lutenizing hormone
How does LH work in females?
ovulation and progesterone secretion
How does LH work in males?
produce testosterone in interstitial cells and stimulates gonads (ovary and testes), activate at puberty
TSH tropic?
yes
ACTH tropic?
yes
FSH tropic?
yes
LH tropic?
yes
GH tropic?
no
PRL tropic?
no
Where are anterior pituitary hormones that are not tropic released from?
acidophil cells
GH
growth hormone
What is another name for GH?
somatotropin
What does GH do?
increased tissue growth, bone and skeletal muscle
Is GH anabolic or exergonic?
anabolic
When do we have the highest production of GH?
in sleep, puberty
What are other factors that regulate growth?
genetics, nutrition, and sexual hormones
What are the 2 conditions that come with hyper secretion of GH?
gigantism and acromegaly
Describe gigantism.
increased GH before epiphyseal plates close, proportionate enlargement
Describe acromegaly.
increased GH after epiphyseal plates closed (affects face-above eye, jaw, hands, feet)- also thick skin, broad nose, enlarged tongue
What is the condition that comes with hypo secretion of GH?
pituitary dwarfism
Describe pituitary dwarfism.
decreased GH, small stature, may be proportionate or not
PRL
prolactin
What does prolactin do?
suckling action; milk production in mammary gland of lactating females
What is the most common reason for excess secretion of PRL?
anterior pit tumor
