Citric Acid Cycle
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23 Terms
Citrate synthase
Enzyme in step 1
aconitase
Enzyme in step 2
Isocitrate dehydrogenase
Enzyme in step 3
alpha-ketpglutarate dehydrogenase complex
Enzyme in step 4
succinyl-CoA synthetase
Enzyme in step 5
Succinate dehydrogenase
Enzyme in step 6
Fumarase
Enzyme in step 7
Malate dehydrogenase
Enzyme in step 8
Acetyl-CoA
Input in CAC
Citrate
Step 1: Acetyl-CoA + Oxaloacetate -----> ?
Isocitrate
Step 2: Citrate -----> ?
alpha-ketoglutarate
Step 3: Isocitrate -----> ?
Succinyl-CoA
Step 4: alpha-ketoglutarate -----> ?
Succinate
Step 5: Succinyl-CoA -----> ?
Fumarate
Step 6: Succinate -----> ?
L-Malate
Step 7: Fumarate -----> ?
Oxaloacetate
Step 8: L-Malate -----> ?
Alpha-ketoglutarate dehydrogenase complex + malate dehydrogenase + isocitrate dehydrogenase
Which steps make NADH
Succinate dehydrogenase
Which steps make FADH2
Succinyl-CoA synthetase
What steps make GTP
3 NADH, 1 FADH2, 1 GTP
What does CAC make
Isocitrate dehydrogenase + alpha-ketoglutarate dehydrogenase complex
what steps release Co2
aconitase (moderate) + L-malate dehydrogenase
Energetic hurdles
Note 
Flashcards (25)