Arsenic

Lewisite Metal

Arsenic is also known as ____________

Salvarsan

• an Antisyphilis also known as Arsphenamine

• also known as compound 606 or magic bullet

• first effective drug against syphylis

Gutzeit’s Test

Identification Test of Arsenic

(modified version of Marsh Test)

Aldrich-mees lines

Acute Poisoning of Arsenic

Manifested by whiter straying in the nails

Rain-drop

Chronic Poisoning of Arsenic

hyperpigmentation of the torso and extremities

Unithiol (DMPS)

1st Line Antidote for Arsenic Toxicity

a water-soluble analog of BAL that is best for acute arsenic poisoning

Dimercaprol Propane Sulfonic Acid

DMPS stands for

Dimercaprol/BAL

2nd Line Antidote for Arsenic Toxicity

Oral Unithiol or Oral Succimer

3rd Line Antidote for Arsenic Toxicity

given once patient is stable

Pb

Arsenic is usually alloyed with __ to make it harder

Trisenox

was introduced for treatment of leukemia

Arsenic Trioxide

• generic name of Trisenox

• primary standard for Ce(SO4)2

• used as rat & ant poison

• used in preparation of Paris Green; Fowler’s Solution; Donovan’s Solution

As2O3

chemical formula for Arsenic Trioxide

Potassium Arsenite Solution

• AKA: Fowler’s Solution

• Formerly used as anti-leukemic

CopperAceto Arsenite

• AKA: Paris Green

• used as insecticide

Donovan’s Solution

red solution containing AsI3 + 1%HgI

Arsine

most toxic form of Arsenic

AsH3

chemical formula or arsine