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find Griffiths transforming principle
bacteria are able to take genetic material from the environment and incorporated into the genetic material
describe Griffiths experiments and what happened to the mice
harmless bacteria could become deadly when mixed with a dead disease causing bacteria making the mice die
what did Avery do in order to further Griffiths discovery
identify the transforming principle as DNA not proteins by isolating different molecules from the bacteria
what was Hershey and Chase experiment and what was concluded from the study
they used infected bacteria and let viruses live on them like concluded that dna what inside the cell but not proteins dna is genetic material
what was Watson and Crick's discovered how are they able to do this
they found that DNA is a double helix photo 51 and built physical models
what did Franklin and Wilkins do what was the importance of this
franklin took photo 51 of DNA structure wilkins show Watson and Creek the photo it helped wants an uncircuit figure out that DNA is a double helix
what are chargaffs rules who discovered them
adenine plus thymine cytosine plus guanine erwin chargaff
What types of bonbs are between bases or as it's important what types of bonds are between the back bones of DNA
Hydrogen bonds they're easier to break carbon bonds
what are the four bases and what are their pairing rules
Adenine thymine cytosine guanine a + t c + g
Which bases are pyrimidine and which bases are purines
A + G are purines C + T are pyrimidines
what is a nucleotide and what makes up a nucleotide what are the differences between the four nucleotides that make up DNA
The building blocks of DNA Sugar phosphate and nitrogenous bases the each have a different base a t c g
and what step of the cell cycle does DNA replication take place
S- synthesis
What is the backbone of DNA made out of the main job of the backbone of DNA
sugar and phosphate to provide structure and support for the molecule
what makes up the rungs of DNA what is the main purpose of the rungs of DNA
the nitrogenous bases to store genetic information
dna is considered to be semi conservative what does this mean
That each DNA molecule is original strand and one newly made strand
What does helicase do in the process of DNA replication
it unzips the DNA strands
what does DNA code for and why is it important
Proteins organisms wouldn't grow function or survive without dna
what does DNA polymerase do in the process of DNA replication in which direction does it work
It builds new DNA strands and ads new nucleotide 5’ to 3’
what does primase do in the process of DNA replication
put a primer flag down for the polymerase to find
what is a primer and why is it important
A short RNA sequence it tells polymerase where to start building bases
What does SSBP do in replication
It binds to the strand to stabilize it
explain the difference between the leading strand and lagging strand
Leading - continuous, 5’-3’
lagging - fragments, 3’-5’, works backwards
Where does DNA replication take place
The cells nucleus
Explain a detail the steps of RNA replication for both waiting and lagging strands of DNA
helicase unzips dna
ssbp stabilizes dna strands
primase lays a primer
polymerase finds primer and lays bases
primase lays primers in fragments
polymerase builds basis in Okasaki fragments
ligase glues fragments together
polymerase proofreads the strands
complimentary strands of t a c t g a
a t g a c t
If 100 bases are present and 45 are g how many are a
45 +45 = 90
100-90 = 10
10/2 = 5 a=5