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Q: What are arteries
A: Vessels that carry blood away from the heart; thick walls, high pressure
Q: What are veins
A: Vessels that carry blood toward the heart; have valves to prevent backflow
Q: What are capillaries
A: Thin, one-cell-thick vessels where gas and nutrient exchange occurs
Q: What is the lumen of a blood vessel
A: The hollow central space through which blood flows
Q: What are metarterioles
A: Short vessels connecting arterioles to capillaries
Q: What do precapillary sphincters do
A: Regulate blood flow into capillaries
Q: What is autoregulation in blood flow
A: Local control of blood flow based on tissue needs (oxygen demand)
Q: What is blood pressure
A: The force exerted by blood on vessel walls
Q: What is systolic pressure
A: Pressure during heart contraction
Q: What is diastolic pressure
A: Pressure during heart relaxation
Q: What is pulse pressure and how is it calculated
A: Systolic – Diastolic; measures artery elasticity
Q: What is mean arterial pressure (MAP)
A: Diastolic + 1/3 Pulse Pressure; average arterial pressure
Q: What is the skeletal muscle pump
A: Muscle contractions push venous blood toward the heart
Q: What is the respiratory pump
A: Breathing movements that help draw blood toward the heart
Q: What is resistance in blood flow
A: Opposition to flow; influenced by vessel length, viscosity, and radius
Q: Why are capillaries exchange vessels, not arteries/veins
A: Capillaries are thin and permeable; arteries/veins are too thick
Q: Why do veins need valves
A: To prevent backflow due to low pressure in veins
Q: What is bulk flow in capillaries
A: Fluid movement driven by hydrostatic & osmotic pressures
Q: What is filtration in capillaries
A: Movement of fluid out of capillaries due to hydrostatic pressure
Q: What is reabsorption in capillaries
A: Fluid reentry due to higher colloid osmotic pressure in blood
Q: What helps venous return
A: Valves, skeletal muscle pump, and respiratory pump
Q: What are the three layers of blood vessels
A: Tunica intima (inner), tunica media (muscle), tunica externa (outer)
Q: Which vessel has a thicker tunica media
A: Arteries
Q: What are elastic arteries
A: Largest arteries; stretch & recoil (aorta)
Q: What are muscular arteries
A: Medium arteries that distribute blood (femoral artery)
Q: What are arterioles
A: Smallest arteries; control flow into capillaries
Q: What are the types of capillaries
A: Continuous, fenestrated, and sinusoidal
Q: Where are continuous capillaries found
A: Skin, muscles, CNS (least permeable)
Q: Where are fenestrated capillaries found
A: Kidneys, intestines (moderate permeability)
Q: Where are sinusoidal capillaries found
A: Liver, spleen, bone marrow (most permeable)
Q: What are venules
A: Small veins that collect blood from capillaries
Q: What are the largest veins
A: Vena cavae, subclavian, jugular
Q: What is the basic order of blood flow
A: Heart → arteries → arterioles → capillaries → venules → veins → heart
Q: What is a portal system
A: Blood flows through two capillary beds before returning to the heart
Q: What are anastomoses
A: Multiple vessels supplying the same area (circle of willis)
Q: What are the methods of capillary exchange
A: Diffusion, vesicular transport, bulk flow
Q: What does the lymphatic system do in blood flow
A: Returns excess fluid to the bloodstream
Q: How is local blood flow controlled
A: By local signals like low oxygen or high CO₂ (autoregulation)
Q: What affects resistance the most
A: Vessel radius (small change = big impact)
Q: How does the nervous system regulate BP
A: Through baroreceptors & brainstem centers; adjusts HR & vessel diameter
Q: What do baroreceptors detect
A: Changes in blood pressure
Q: Which hormones raise BP
A: Epinephrine, ADH, aldosterone
Q: Which hormone lowers BP
A: ANP (Atrial Natriuretic Peptide)
Q: How does the hepatic portal system work
A: Blood from digestive organs → liver → filtered → systemic circulation
Q: How do you calculate MAP
A: MAP = Diastolic + ⅓(Systolic – Diastolic)