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Glycogen
Made of glucose, animal starch
Hypoglycemia
Low blood glucose levels
Hyperglycemia
High blood glucose levels
Hormone synthesized and secreted by B cells
Insulin
Hormone synthesized and secreted by A cells
Glycogen
Glycogenesis
Glucose synthesized to ATP/glycogen, causes decreased glucose levels
Glycogenolysis
Degradation glycogen to glucose, causes increased glucose levels
Gluconeogenesis
Synthesis of amino acids to glucose, causes increased glucose levels
Lipogenesis
Synthesis of glucose to glycerol, causes decreased glucose levels
Lipolysis
Degradation of triglycerides to free fatty acids and glycerol, causes no change to blood glucose levels
Insulin in facilitated diffusion of glucose
Some organs and cells need the presence of insulin in order to bring glucose across the membrane
Insulin's effect on glucose levels
Decreases blood glucose levels
Stimulus for insulin release
High blood glucose levels
Metabolic processes that are stimulated by/require the presence of insulin
Glycogenesis, glycogenolysis, lipogenesis
Glucagon effect on blood glucose levels
Increases blood glucose levels
Stimulus to release glucagon
Low blood glucose levels
Effect of glucagon in the liver
Glycogenolysis and gluconeogenesis
Insulin:glucaon ratios vary based on
metabolic state (feeding vs. fed)
Epinephrine effect on blood glucose levels
Increase blood glucose levels
Stimulus that causes release of epinephrine
Decreased blood glucose levels
Organ that releases and synthesizes epinephrine
Adrenal medulla
Metabolic process stimulated by epinephrine
Glycogenolysis
Glucosuria
Glucose present in urine
Polyuria
Large quantities of water excreted duw to glucosuria
Polydipsia
Excessive water intake, caused by polyuria
Acidosis
Metabolization of fat because of an inability to metabolize glucose
Type I diabetes cause
Pancreas is not producing sufficient insulin
Type II diabetes cause
Insulin receptors are not functioning
Type I diabetes onset
<20
Type II diabetes onset
>40
Type I diabetes treatment
Insulin injections
Type II diabetes treatment
Dietary control and weight loss
Insulin shock cause
Hypoglycemia
Diabetic coma cause
Hyperglycemia
Recommendation of ADA for diabetes screening
Blood test by 45 years and testing every 3 years after that
Which photoreceptor is responsible for night vision?
Rods
Which photoreceptor is responsible for color vision?
Cones
Fovea
Pit with highest concentration of cones, inner layers of retina brushed aside so its unobstructed
Periphery
Higher concentration of rods than cones
Blind Spot
Where there are no rods or cones because the optic nerve is there
2 factors that determine the power of a lens
1. Curvature of lens
2. Differences in refraction between media
4 Components of the Refractive System of the Eye
1. Cornea
2. Aqueous humor
3. Lens
4. Vitreous humor
Which interface causes the greatest refraction?
Cornea
Focal Point of Lens
The point at which light is focussed
Where must the focal point be for a clear image?
On the retina
Focal Length
Distance between the lens and the focal point
Convex Lens
Converges light, + diopter
Concave Lens
Diverges light, - diopter
Refractive power=
1/Focal length (m)
Emmetropia
Normal vision, .017mm, 59 diopters
3 Reflexes associated with the Near Response
1. Accommodation Reflex
2. Pupillary Reflex
3. Convergence Reflex
What does the accommodation reflex do to the power of the eye lens?
Increases
Why is it necessary to focus the image of a near object on the retina?
So the image is clear
Role of ciliary muscle during accommodation?
Relaxes
Role of sensory ligaments during accommodation?
Tension increases
Which branch of the ANS is responsible for contraction of the ciliary muscle?
Increased PANS
Which branch of the ANS is responsible for relaxation of the ciliary muscle?
Decreased PANS
What type of muscle is ciliary muscle?
Multi-unit smooth muscle
Are light rays parallel or diverging as they enter the eye from a distant source?
Parallel
Are ciliary muscles contracted or relaxed with distant vision?
Relaxed
Are light rays parallel or diverging as they enter the eye from a near source?
Diverging
What must happen to the lens as one moves their gaze from a distant to a near object?
Increase refractive power
What happens to the elasticity of the lens and therefore the ability to increase refractive power as one ages?
Decreases
Presbyopia
Impaired vision as a result of aging
Presbyopia: does the nearpoint of vision increase or decrease?
Decrease
Where is the focal point for presbyopia?
Behind the retina
What type of lens corrects presbyopia?
Convex lens
Pupillary Reflex
Accommodates varying light levels by dilating or constricting, visual acuity
How does the pupillary reflex help focus a near object's image on the retina?
By excluding more divergent rays
Which branch of the ANS is responsible for active pupillary dilation?
Increased SANS
Which branch of the ANS is responsible for active pupillary constriction?
Increased PANS
What type of muscle is the iris?
Multi-unit smooth muscle
How does convergence help with near vision?
Moves both eyes inward to achieve a single image
What branch of the nervous system is responsible for contraction of ocular muscles?
Somatic nervous system
What are 2 potential causes of hyperopia?
1. Flattened lens/cornea
2. Short eyeball
Where is the focal point in uncorrected hyperopia?
Behind the retina
What lens corrects hyperopia?
Convex (+)
What are 2 potential causes of myopia?
1. Increased curve of lens/cornea
2. Long eyeball
Where is the focal point in uncorrected myopia?
In front of the retina
What lens corrects myopia?
Concave lens (-)
How does Snellen's chart help determine the visual acuity of a subject?
By having them read letters that decrease in size that have corresponding values for how well they can see
20/X, top and bottom relation
Top-What subject can see at 20 feet
Bottom-What a "normal person" can see at X feet
Astigmatism
Defective curvature of the cornea or lens of the eye
What are 2 potential causes of astigmatism?
1. Unusual curvature of cornea/lens
2. Abnormal refraction at either axis
How does the astigmatism chart help diagnose the condition?
By having outspreading lines, it'll show if some areas of vision are blurry while others are not by providing various angles and axes
Why can hard lenses be used to treat astigmatism but not soft?
Because the hard lens fills in the abnormal curves of the cornea while a soft lens cannot
Antigen
On cell, determines blood type
Antibody
In plasma, protective response against foreign antigens
Immune Complex
Antigen/antibody combined complex
Blood Group System
Different types of blood
Transfusion
RBC only
Transfusion Reaction
Agglutination of RBC with Rh antibodies
Donor
Person who gives blood
Recipient
Person who receives donated blood
Whole blood
RBC, plasma, antibodies
Packed Cell
RBC without plasma
In vitro
Within the body
In vivo
Within artificial
What antigens are associated with the ABO blood system?
Red cell antigen
Antibodies/Antigens: Type A
Antibody: b
Antigens: A