Histology of Salivary Gland

Differentiate Serous and Mucous Glands

• Nucleus

• Secretion

Serous:

• Nucleus: Round and circular

• Secretion: Thinner

Mucous:

• Nucleus: Flattened and basal

• Secretion: Thicker

• Cytoplasm: Foamy

Salivary Glands

• Consist of

• Originate from

• 3 major salivary glands

  • Type of secretory cell

Consist of: Series of secretory units (glandular epithelium)

Originate from: Oral ectoderm, but grows in to underlying mesoderm

3 major salivary glands:

• Parotid

  • Secretory cell: Serous

• Sublingual

  • Secretory cell: Mucous

• Submandibular

  • Secretory cell: Mixed

Histological Structure of Salivary Gland

• What divides each lobules

• What is lobule made up of

• Types of ducts

What divides each lobules: Connective tissue capsule

What is lobule made up of: Secretory unit

Types of ducts: Intralobular and Interlobular

Intralobular vs Interlobular Duct

• Location

• Types

• Function

• Histology

Intralobular Duct:

• Location: Inside lobule

• Types: Intercalated and striated ducts

• Function:

  • Intercalated: Collect secretions

  • Striated: Modify secretions

• Histology: Simple cuboidal (one layer of cells)

Interlobular Duct:

• Location: Between lobules

• Function: Collects from multiple intralobular ducts and transports it towards main excretory duct

• Histology: Stratified columnar (multiple layers of cell)

Salivary Gland: Parotid Gland #ff8e00

• Compose of what secretory unit

• Lobules separated by

  • Contains

• Secrete into

  • Lined with

Compose of what secretory unit: Serous secretory unit

Lobules separated by: Loose connective septa

• Contains:

  • Nerves

  • Blood vessels

  • Larger secretory ducts

Secrete into: Intercalated ducts

• Lined with: Low cuboidal epithelium

Salivary Gland: Submandibular Gland

• Type of secretion

• Lobules separated by

  • Contains

• Which cells form main lining

• Which cells form periphery lining

  • When grouped together, they are called

• Each secretory unit surrounded by

  • Function

Type of secretion: Mixed, either serous or mucous

Lobules separated by: Loose connective septae

• Contains:

  • Nerves

  • Blood vessels

  • Secretory ducts

Which cells form main lining: Mucous secreting cells

Which cells form periphery lining: Serous secreting cells

• When grouped together, they are called: Serous demilune

Each secretory unit surrounded by: Contractile myoepithlial cells

• Function: Contract and squeeze contents of lumen into duct