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Bone marrow…what does it do?
-Produces none marrow stem cells and blood products
-Hematopoiesis
-Lymphocytes are produced in marrow to help immune system
Hematopiesis
The process of bone marrow creating RBCs, WBCs, and plateletes
Bone Marrow…what is it?
RBCs carry O2 and nutrients
WBC fight infections
Platelets help with coagulation
Bone marrow transplant…why?
-Leukemia
-chemotherapy
-Aplastic anemia
-Congenital neutropenia
-Sickle Cell anemia
-Thalassemia
Bone marrow transplant…complications??
Graft-versus-host disease (GVHD)
graft failure
Cataracts
Anemia
Infections
Mucositis
Mucositis
All mucous membranes become inflamed
Graft vs. Host
Type IV
Delayed reaction that occur when T cells recruit macrophages and attack foreign body or tissue