Cell Metabolism Final

Given the list below, select atoms that are required in trace amounts by humans

Fe, Co, Se, Mg, V, Cu, Zn, Mo, I, Cr, Mn, Ni

Given the list below, select atoms that are required in abundance amounts by humans

CHON KClPS NaCa

C, H, O, N, K, Cl, P, S, Na, Ca

What is primary role for nucleic acids?

information storage

What is primary role for liver?

maintaining blood sugar

What is primary role for muscle?

energy for cell

What is primary role for proteins/enzymes?

action, catalysis

What is primary role for lysosomes?

cellular digestion

What is primary role for cytosol?

metabolism of carbs, primary site of protein synthesis, structural support for organelles

a patient at 6 months presents with severe accumulation of lips in many tissues and especially liver. If choices are Wolman’s disease and Cholesterol Ester Storage Disease. What is this diagnosis?

not enough information because younger than 1

a patient at 2 years presents with severe accumulation of lips in many tissues and especially liver. If choices are Wolman’s disease and Cholesterol Ester Storage Disease. What is this diagnosis?

CESD - cholesterol ester storage disease

What biomolecule is used metabolically as energy source

all biomolecules used as energy source

What biomolecules plays largest role in cellular structures such as membranes?

lipids

What biomolecules plays largest role in energy?

carbs

What biomolecules plays largest role in muscles?

glycogen, carbs

What biomolecules plays largest role in action?

protein, enzymes

Which cellular compartment houses enzymes related to Wolman’s disease and CESD

lysosome

Which pathway was first identified as conserved across multiple species that provided this information?

glycolysis

Which cellular compartment is used for ATP production?

mitochondria

Which cellular compartment is used for protein production?

cytosol, ribosomes

Which cellular compartment is used for membrane-bound proteins

rough ER

Which cellular compartment is used for fatty acids?

smooth ER

Examining the genetics of Wolman’s disease, what is expected?

premature stop codon

Examining the genetics of CESD, what is expected?

G to A mutation, exon splicing error

What make a steady-state system different from an equilibrium system

steady-state systems attempt to restore the product-reaction ratio

TRUE

TRUE OR FALSE: At equilibrium, the reaction has halted

FALSE

TRUE OR FALSE: In general, most but not all enzymes are capable of reverse activity

TRUE