Key Enzymes in Prokaryotic DNA Replication (E. coli)
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9 Terms
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DnaA
Binds origin (oriC), melts DNA to start replication
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Helicase (DnaB)
Unwinds double helix
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SSBs (Single-Strand Binding Proteins)
Keep strands apart
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Primase
Lays down RNA primer
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DNA Polymerase III
Main synthesis enzyme
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DNA Polymerase I
Removes RNA primer, fills in DNA
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DNA Ligase
Seals gaps (Okazaki fragments)
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Topoisomerase (gyrase)
Relieves supercoiling ahead of fork
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Sliding Clamp (β-clamp)
Increases processivity of DNA Pol III
Note 
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