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Neuron
A nerve cell that transmits electrical and chemical messages. Ex: Sensory neurons carry signals from your skin to your brain.
Sensory neurons
Carry information from sensory receptors to the brain/spinal cord. Ex: Detecting heat from a stove.
Motor neurons
Send signals from the brain/spinal cord to muscles or glands. Ex: Moving your hand off the stove.
Interneurons
Connect sensory and motor neurons within the brain/spinal cord. Ex: Spinal interneurons trigger reflexes.
Glial cells
Support, nourish, and protect neurons. Ex: Schwann cells form myelin in the PNS.
Resting potential
The neuron’s stable, negative charge when inactive. Ex: Around –70 mV inside the axon.
All-or-nothing principle
A neuron fires completely or not at all. Ex: Pressing the threshold triggers a full impulse.
Reuptake
Neurotransmitters are reabsorbed by the sending neuron. Ex: SSRIs block serotonin reuptake to treat depression.
Refractory period
Time after firing when a neuron can’t fire again. Ex: Prevents overlapping impulses.
Threshold
Minimum stimulation needed to trigger an impulse. Ex: Enough depolarization causes action potential.
Depolarization
Positive ions enter the neuron, making it more likely to fire. Ex: Sodium ions rushing in.
Neurotransmitter
Chemical messenger across the synapse. Ex: Dopamine influences movement and pleasure.
Excitatory neurotransmitter
Increases likelihood of neuron firing. Ex: Glutamate.
Inhibitory neurotransmitter
Decreases likelihood of neuron firing. Ex: GABA.
Agonist
Mimics neurotransmitter effects. Ex: Morphine mimics endorphins.
Antagonist
Blocks neurotransmitter effects. Ex: Botox blocks acetylcholine.
Acetylcholine (ACh)
Enables muscle movement and memory. Ex: Low ACh in Alzheimer’s.
GABA
Main inhibitory neurotransmitter. Helps regulate anxiety, fear, and stress by making neurons less likely to fire, which can promote a sense of calm, improve sleep, and stabilize mood.
Serotonin
Regulates mood, hunger, and sleep. Ex: Antidepressants increase serotonin.
Dopamine
Influences movement and reward. Ex: Too much = schizophrenia; too little = Parkinson’s.
Endorphins
Natural painkillers and mood boosters. Ex: Released during exercise (“runner’s high”).
Norepinephrine
Controls alertness and arousal. Ex: Low levels = depression.
Glutamate
Main excitatory neurotransmitter; involved in learning. Ex: Too much can cause migraines.
Substance P
Transmits pain signals. Ex: High levels during injury.
Multiple Sclerosis (MS)
Myelin sheath degenerates, slowing signals. Affects the central nervous system, and symptoms can vary widely. Ex: Causes muscle weakness.
Myasthenia Gravis
Immune system attacks ACh receptors. Ex: Leads to muscle fatigue.
Lesions
Destroyed brain tissue used to study function. Ex: Lesioning amygdala affects fear.
fMRI (Functional MRI)
Tracks brain activity via blood flow. Ex: Shows active areas during speech.
EEG (Electroencephalogram)
Records electrical brain activity. Ex: Detects sleep stages.
Brainstem
Controls basic life functions. Ex: Breathing and heartbeat.
Medulla
Regulates heartbeat, swallowing, and breathing. Ex: Damage can cause death
Reticular activating system
Controls arousal and attention, filters information, connects to nerve network. Ex: Helps you wake up.
Cerebellum
Coordinates voluntary and involuntary movement and balance, nonverbal learning/memory, and processes sensory input. Ex: Playing the piano smoothly.
Limbic system
Emotion and motivation center, memory formation. Ex: Includes amygdala and hippocampus.
Thalamus
Sensory relay station to the cortex (all senses except for smell). Ex: Sends visual info to occipital lobe.
Hypothalamus
Regulates bodily maintenance: hunger, thirst, body temp, and drives. Dopamine production, influences in pituitary gland, the four f’s. Ex: Triggers eating when hungry.
Hippocampus
Forms new memories, navigational abilities, helps process explicit/concious memories (facts/events) for storage. Ex: Damage causes amnesia.
Amygdala
Processes intense fear and aggression (emotional memories/experiences). Ex: Overactive amygdala = anxiety.
Split brain procedure
Cuts corpus callosum to reduce seizures. Ex: Right/left hemispheres act independently.
Corpus callosum
Connects brain hemispheres. Communication link! Ex: Integrates functions of both sides.
Occipital lobe
Visual processing cortex. Ex: Damage = blindness/visual hallucinations/distortions.
Parietal lobe
Processes touch and body position, contains somatosensory cortex. Ex: Sensing texture or temperature.
Frontal lobe
Controls planning, judgment, impulse control, social behavior, higher order thinking, and movement. Contains motor cortex. Ex: Used in decision making.
Temporal lobe
Processes hearing and language. Ex: Damage = hearing loss.
Somatosensory cortex
Processes body touch/movement sensations, at the front of the parietal lobes. Ex: Feeling pressure on skin.
Motor cortex
Controls voluntary movements. Ex: Moving your right arm.
Broca’s area
Produces speech. Ex: Damage = trouble speaking/broken sentences.
Wernicke’s area
Comprehends language. Ex: Damage = meaningless speech.
Plasticity
Brain’s ability to reorganize after damage. Ex: Stroke recovery.
Peripheral nervous system (PNS)
Connects CNS to the rest of the body. Ex: Nerves in limbs.
Somatic nervous system
Controls voluntary movement. Ex: Lifting a glass of water.
Autonomic nervous system
Controls involuntary actions. Ex: Heartbeat and digestion.
Sympathetic nervous system
Activates “fight or flight.” Ex: Increased heart rate during stress.
Parasympathetic nervous system
Calms body after stress. Ex: Slows heartbeat after fear passes.
Pituitary gland
Controlled by hypothalamus. Master gland controlling other glands; releases growth hormone. Ex: Oversees puberty hormones.
Adrenaline (epinephrine)
Hormone that boosts alertness and energy in stress. Ex: Adrenaline rush before a race.
Right Hemisphere Functions
Controls the left hand
Nonverbal
Visual-spatial perception
Music and artistic processing
Emotional thought and recognition
Processes the whole
Pattern and facial recognition
Left Hemisphere functions
Controls the right hand
Spoken/written language
Mathematical calculations
Logical thought processes/analysis of details
Reading/making lists