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Physiology of BP (3)
Without enough BP, tissues will not receive needed oxygen and nutrients
However, high BP strains the heart and will eventually cause heart failure
Arterial BP can change w/o affecting venous BP so must measure all BP’s
3 Factors that Control BP
Heart
Blood
Vessels
Control of BP - Factor 1 (Heart) (2)
Pump that creates pressure gradient
Changes in the heart itself will directly affect BP:
Decr. HR or strength of contraction → BP decreases
Incr. HR or strength of contraction → BP increases
Control of BP - Factor 2 (Blood) (1)
Amount of fluid in circulatory system affects BP:
Incr. blood volume → BP increases
Decr. blood volume → BP decreases
Control of BP - Factor 3 (Vessels) (1)
Tone of the blood vessels affect BP:
Vasoconstriction → BP increases
Vasodilation → BP decreases
What is used to increase HR? (2)
Epinephrine
Atropine
What is used to decrease HR? (1)
Beta blockers (lol)
What is used to increase blood volume? (1)
IV fluids
What is used to decrease blood volume? (1)
Diuretics
What is used to increase vessel tone? (1)
Epinephrine
What is used to decrease vessel tone? (2)
Ace inhibitors (“pril”)
Nitroglycerin
Systemic Arterial BP Waveform (2)
Normal 120/80
Dicrotic notch represents closure of the aortic valve
Rule of 4’s
Heart has 4 chambers
Each chamber serves 1 of the 4 circulatory branches:
LV - systemic arteries
RA - systemic veins
RV - pulmonary arteries
LA - pulmonary veins
Each chamber and connecting artery or venous system has its own BP - 4 pressures
LV - systemic arteries - arterial BP
RA - systemic veins - CVP
RV - pulmonary arteries - PAP
LA - pulmonary veins - PCWP
Hemodynamic measures each of these pressures
CVP, RAP, RVEDP, RV preload (6)
Measures pressure in the systemic venous system
Much lower than mean ABP
Since most of blood is in the venous system, changes in the CVP reflect changes in vascular volume so →
CVP used to monitor vascular fluid levels and right heart function
Treat when > 12 mmHg
Transducer at level of RA
PAP (2)
Measures blood moving through the pulmonary arteries into the lungs
Increases in PAP occur in lung disease → increased PVR
PCWP, PWP, PAOP, LAP, LVEDP, LV preload (4)
When BTFDC “wedged” - no longer measures forward flow of blood
Measures back pressure from pulmonary veins which are in direct communication with left heart
PCWP monitors left heart (LV and mitral valve)
Treat when > 12 mmHg (pulmonary edema with a sick heart, for a normal and healthy heart, greater than 18 you’ll start seeing pulmonary edema)
Condition CVP PAP PCWP and QT for Right Heart
Increased CVP
(N) or decreased PAP
(N) or decreased PCWP
(N) or decreased QT
Condition CVP PAP PCWP and QT for Lung Problems
Increased CVP
Increased PAP
(N) or decreased PCWP
(N) or decreased QT
Condition CVP PAP PCWP and QT for Left Heart
Increased CVP
Increased PAP
Increased PCWP
Decreased QT
Condition CVP PAP PCWP and QT for Hypervolemia
Increased CVP
Increased PAP
Increased PCWP
Increased QT
Condition CVP PAP PCWP and QT for Hypovolemia
Decreased CVP
Decreased PAP
Decreased PCWP
Decreased QT
Hansen’s Helpful Hint #1 (2)
Increased PAP + normal PCWP = lung disease
Increased PAP + Increased PCWP = left heart problems
Hansen’s Helpful Hint #2 (1)
PAd - PCWP: If > 5 mmHg = increased PVR
Hansen’s Helpful Hint #3 (1)
PCWP cannot be > PAd
Helpful Hint #4 (1)
Hypovolemia is the only condition that will decrease your pulmonary capillary wedge pressure
Trivia to Remember (5)
Preload = ventricular filling volume/pressure
Afterload = pressure after
BTFDC tip should lie in a Zone III artery
QT decreased → O2 extraction increased → PvO2, SvO2 decreased, CvO2 decreased → C(a-v)O2 increased
SvO2 is the best indicator of tissue oxygenation
Normal MAP (Mean Arterial Pressure)
93-94 mmHg
Normal CVP (Central Venous Pressure)
2-6 mmHg
4-12 cmH2O
Normal PAP (Pulmonary Artery Pressure) and Normal mean PAP
PAP: 25/8 mmHg
Mean PAP: 13-14 mmHg
Normal PCWP (Pulmonary capillary wedge pressure)
4-12 mmHg