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Where does pyruvate go after glycolysis?
Into the mitochondrial matrix
What happens to pyruvic acid when it enters the mitochondrial matrix?
NAD⁺ accepts 2 high‑energy electrons and 2 H⁺ to form NADH + H⁺
How many CO₂ molecules are released during pyruvate conversion?
2 CO₂ (1 per pyruvate)
What happens to the remaining 2‑carbon fragment of pyruvate?
It becomes acetate
What does acetate combine with?
Coenzyme A
What molecule is formed when acetate joins Coenzyme A?
Acetyl‑CoA
What is acetyl‑CoA's role?
It enters the Krebs cycle
What are the reactants of pyruvate conversion?
2 molecules of pyruvate
What are the products of pyruvate conversion?
2 CO₂; 2 NADH + H⁺; 2 acetates (which join CoA to form acetyl‑CoA)
Why does pyruvate conversion matter?
It produces acetyl‑CoA, the molecule required to start the Krebs cycle