Studied by 0 people
Looks like no one added any tags here yet for you.
Jules Bordet
scientist who first identified complement system with sheep and cholera
complements
specific function of these types of proteins is to puncture cell membranes
zymogen
name for inactive form of complements
membrane attack complex
association of C5b, C6, C7, C8, and C9
C8
part of membrane attack complex, quaternary structure made up of 2 subunits (beta and alpha-gamma)
C9
makes up the bulk of the membrane attack complex
C3aR and C5aR
two receptors that function in anaphylatoxin signaling (stimulates inflammation with granulocytes)
C5L2
suppressor modulator that binds C5a to inhibit C5aR binding
IL-6 and TNF-alpha
activated by complement system to promote inflammation and fever
sialic acid
recognized and bound by the complement system on T-cells to activate them
contraction phase
phase that occurs after an immune response, characterized by decrease of immune cells and removal of debris
phosphatidylserine
phospholipid that can be inverted in dead cell membranes to signal removal from body
eculizumab
example of a medicine that uses membrane attack complex/complements
Note 
Flashcard (100)