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What is a symptom of mucosal damage?
A reflux of gastric acid, pepsin, trypsin and bile in the lower esophagus
What is the irritation and inflammation called?
Esophagitis
What is a major risk?
Obesity
What is the cause of GERD?
A weak or incompetent lower esophageal sphincter
Some food contributors to GERD?
Alcohol, smoking, chocolate, fatty food, caffeine, peppermint, spearmint
What medications are contributors to GERD?
Anticholinergics, beta blockers, calcium channel blockers, diazepam (valium), morphine sulfate, nitrates, theophylline and progesterone
Some of the clinical manifestations of GERD?
Heartburn, dyspepsia, regurgitation, respiratory symptoms and a hoarseness or lump in the throat, choking
When is heartburn or pyrosis concerning?
There are persistent to mild symptoms more than twice a week and moderate to severe symptoms once a week
How is dyspepsia described?
A pain in the upper abdomen
Possible respiratory symptoms?
Wheezing, coughing and dyspnea
When do some CM need further evaluation?
severe heartburn
heartburn > 2x a week
heartburn with dysphagia
occurs at night
awakens person from sleep
older person with recent onset of heartburn
Why is it important to look further into older individuals with these concerns?
The heartburn could potentially be a cardiac issue that would need checking out
Some complications that can be experienced?
Esophagitis, ulcers, Barrett esophagus and fibrosis, scarring
What group of people mostly experience Barrett esophagus?
Those who may be centrally obese and white men over the age of the 60
What is an extreme risk for those with Barrett esophagus?
Increased risk of cancer
What is experienced with fibrosis and scarring?
Strictures and dysphagia
What is strictures?
The narrowing of the esophagus
What diagnostic studies can be done for GERD?
Endoscopy, biopsy, manometric studies and esophageal pH monitoring
What does an endoscopy look for?
LES competence and any inflammation, scarring and strictures
What is observed for in a biopsy?
Dysplasia
How are manometric studies applied?
Looks for pressures and any motility
How high do we want to elevate the HOB?
By 30 degrees
can also use pillows to 4 to 6 inch blocks
How long after a meal should you avoid laying down?
2 to 3 hours
Why should you avoid bending over?
Can cause more acid reflux and lead to vomiting
Should you wear tight fitting clothes around your waist?
No
How many hours before bed should you stop eating?
3 hours
What is the biggest thing we want to stop?
Smoking
Why is reducing stress levels important?
Increases your cortisol levels and causes more acid to be made
Why is it important to increase your physical activity level?
This lowers the obesity risk and increase GI motility
also eat a low fat diet
What are some ways that distention of the stomach can be avoided?
By eating small frequent meals which is about 4-6 meals a day
What types of beverages should be avoided?
Alcohol, caffeine and acidic beverages
What drugs decrease volume and acidity of reflux?
H2 receptor blockers and proton pump inhibitors
What is a goal of H2 receptor blockers?
Inhibits the parietal cells for making hydrochloric acid
How do the H2 receptors work?
onset of action: 1 hr
lasts 12 hrs
can be combined with an acid
How should proton pump inhibitors be administered?
Once daily dosing
Take before the first meal of the day
What are some of the long term effects of taking a proton pump inhibitor?
Decreased bone density, kidney disease, vitamin b12 and magnesium deficiency
What are adjunct medications?
Antacids
What is the goal of antacids?
To neutralize acid
Patient teaching with antacids?
1-3 hours after meals and bedtime
Effects last 3 to 4 hours
Relieve heartburn for 20 to 30 minutes
Take before bed and when you really need it
How does prokinetic drug therapy work?
Increases the LES pressure, increases gastric emptying and increases gastric motility
meds: Reglan and Metoclompramide (increases the gut)
What foods should you stay away from so that LES pressures aren’t decreased?
Chocolate, peppermint, fatty foods, coffee and tea
Caffeine, alcohol, acids foods and liquid are all what?
Irritants
What can occur when you eat too late, have a nighttime snack or drink milk at bedtime?
There will be an increase in gastric acid secretion
To prevent stomach distention?
have small frequent meals
Drink fluids between meals
How can we increase our saliva production?
Chewing gum
Different ways that Laparoscopic Surgical Therapy can work?
Enhances LES integrity
Wrap the fundus of stomach around the esophagus
LINx Reflux Management System
Goal of enhancing the LES integrity?
protects against reflux
What is fundoplication and what should be done post-operatively?
The fundus of the stomach is wrapped around the esophagus to stop stomach acid from flowing back up
Dysphagia for the first month post operatively
How does the LINX Reflux Management System work?
There are magnets in titanium rods that are connected by titanium wires
Helps to keep the LES closed (nausea, swallowing problems and pain when swallowing food)
What is a big no no with the LINX system?
MRI’s (due to magnets)
What does an endoscopic therapy do?
Thickens the LES
Endoscopic mucosal resection
Radiofrequency ablation
What is a hiatal hernia?
portion of the stomach that protrudes up through the opening in the diaphragm
A type 1 hernia?
There is prolonged exposure
can slide
GEJ through diaphragm when supine
Acid Reflux (Barrett’s esophagitis)
Strictures
Dysphagia
Erosions (cameron lesions)
A type 2 hernia?
Will create a pocket within the esophagus
can roll
Fundus of stomach through diaphragm (pocket alongside the esophagus)
Fullness after eating, breathless after eating, chest pain
Volvulus and obstruction
What is ascites?
A 3rd spacing of fluid in abdomen
Pathophysiology of hiatal hernias?
weakening of muscles in the diaphragm
Aging (due to muscles not being as strong anymore)
Increased intra-abdominal pressure (ex: obesity, pregnancy, ascites, tumors, physical exertion, heavy lifting
Clinical Manifestation for hiatal hernia?
This is comparable to GERD symptoms
Acid is in the stomach where it should not be
Complications of hernias?
Esophagitis, bleeding from erosion, stenosis, ulceration of herniated portion of stomach
Strangulation of hernia (loss of blood supply to that area of the stomach)
Regurgitation with tracheal aspiration (aspirational pneumonia)
Esophagitis is?
inflammation of the esophagus
Ulceration of herniated portion of stomach is?
Portion of stomach in the esophagus
Some ways to reduce intra-abdominal pressure?
no constricting clothing
No lifting/Straining
Antacids do what?
Neutralize acid
H2 receptor blockers?
Reduce acid production
Famotidine (Pepcid)
Proton Pump Inhibitors
Block acid production
Omeprazole (Prilosec OTC)
What is done with a laparoscopic procedure?
Nissen/Toupet Fundoplication
Top of the stomach is wrapped around the esophagus
Higher recurrence rate
What can be done during an open procedure?
Gastropexy
Herniotomy
Herniorrhaphy
Gastropexy is?
Attaching the stomach below the diaphragm
Herniotomy is?
Removing the herniated sac
Herniorrhaphy is?
Repairing and/or closing the hiatal defect
What is the main muscle of respiration?
Diaphragm
Things to watch post-operatively?
Clots
Things related to the chest in regard to venous return
Watch age- as it can be riskier for some individuals
Nursing interventions to consider?
Sleep with HOB elevated
Lose weight (decrease abdominal pressure)
Avoid tobacco and alcohol
Reduce Stress
Things that should be assessed?
Heartburn
Regurgitation
Dysphagia
Belching
Breathlessness
Why is there concern with older adults?
At an increased risk
Increased abdominal pressure due to weakened diaphragm, obesity and kyphosis
Take meds that decrease LES pressure; nitrates, CCB, antidepressants
Not as active to move around anymore