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Lymph
Fluid that circulates through lymphatic vessels, containing water, proteins, and immune cells.
Lymphatic Vessels (Lymphatics)
Vessels that carry lymph from tissues to the bloodstream.
Lymph Node
Small bean-shaped structures that filter lymph and house immune cells.
Spleen
An organ that filters blood, removes old red blood cells, and supports the immune system.
Thymus
An organ where T lymphocytes (T cells) mature and become immunocompetent.
Tonsils
Lymphoid tissues in the throat that trap pathogens entering through mouth or nose.
Peyer's Patches
Lymphoid tissues in the small intestine that monitor intestinal bacteria and prevent pathogen growth.
Interstitial Fluid
Fluid that surrounds tissue cells and delivers nutrients and oxygen.
Edema
Swelling caused by excess fluid in tissues.
Pathogen
A microorganism that can cause disease.
First Line of Defense (Skin
Mucous Membranes),Physical and chemical barriers that prevent pathogens from entering the body.
Second Line of Defense
Immune responses such as inflammation, phagocytosis, and fever after pathogens enter the body.
Phagocyte
Cells that engulf and digest pathogens and cell debris.
Phagocytosis
The process by which phagocytes engulf and digest microorganisms or particles.
Macrophage
A large phagocyte that engulfs pathogens, dead cells, and signals the immune system.
Neutrophil
A white blood cell that rapidly responds to infections and performs phagocytosis.
Natural Killer (NK) Cells
Lymphocytes that attack virus-infected and tumor cells without prior exposure.
Inflammation
A localized response to injury or infection causing redness, heat, swelling, and pain.
Fever
An elevated body temperature that enhances immune responses and inhibits pathogen growth.
Antimicrobial Proteins
Proteins that attack pathogens or interfere with their reproduction.
Interferons
Proteins released by virus-infected cells that signal nearby cells to resist viral infection.
Complement Proteins
Proteins in the blood that assist antibodies in destroying pathogens.
Adaptive (Specific) Immunity
Immune response that targets specific pathogens and retains memory for future exposure.
Antigen
A substance that triggers an immune response and is recognized by antibodies or T cells.
Antibody (Immunoglobulin - Ig)
A protein produced by B cells that binds to a specific antigen to neutralize or mark it for destruction.
B Lymphocyte (B Cell)
A white blood cell that produces antibodies as part of humoral immunity.
T Lymphocyte (T Cell)
A white blood cell that performs cellular immune responses including killing infected cells or helping other immune cells.
Plasma Cell
A mature B cell that produces large amounts of antibodies.
Memory B Cell
A B cell that remembers a specific antigen and responds rapidly upon future exposure.
Helper T Cell
A T cell that activates B cells, cytotoxic T cells, and other immune cells.
Cytotoxic T Cell
A T cell that kills virus-infected or cancerous cells.
Memory T Cell
A T cell that remembers antigens and mounts a faster response on re-exposure.
Immunological Memory
The ability of the immune system to respond more rapidly and effectively to a previously encountered antigen.