8.3: Enzymes and Energy - Inhibition and Allosteric Regulation

allosteric regulation

occurs when nonsubstrate binds to a site other than active site inducing enzyme to change shape = alters active site’s affinity for substrate and rate of reaction changed

2 shapes of enzyme

active form = has proper shape for substrate binding

inactive form = has shape that substrate can’t bind to

regulatory site

a site on an enzyme where regulatory molecules can bind, affecting the enzyme's activity and shape.

activator vs inhibitor

Activators enhance enzyme activity by promoting the active form, while inhibitors decrease activity by stabilizing the inactive form.

allosteric enzymes

A type of enzyme that has multiple binding sites, allowing them to change shape and activity in response to the binding of regulatory molecules.

why is allosteric regulation important in regulation of metabolism

allows enzymes to be finely tuned to meet the needs of the cell. This flexibility helps regulate metabolic pathways efficiently in response to changing cellular conditions.