Bacterial Genomes and DNA Replication

0.0(0)
studied byStudied by 0 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/7

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

8 Terms

1
New cards

What is a genome?

The entire compliment of of an organism’s genes - looks at genetic potential, organism relationships, virulence factors, and anti-microbial targets

2
New cards

The limitation of genomes?

It won’t tell us what genes are expressed at a given time

3
New cards

What can genome sequencing tell us?

It outlines the genetic potential of organisms; functions are assigned to genes (38.1% of e.coli genes have unknown functions)

4
New cards

ORFs

“open reading force” - gene sequence predicted to code for a protein (note the positive/negative correlations in the diagram)

<p>“open reading force” - gene sequence predicted to code for a protein (note the positive/negative correlations in the diagram)</p>
5
New cards

Characteristics of bacterial chromosomes

  • Most are circular, covalent closed

  • cells are haploid

  • DNA is condensed in nucleoid

  • One origin of replication

  • Most DNA sequence codes for proteins: “compact” genome (ex. intrams)

6
New cards

Central Dogma/Gene expression

DNA → mRNA → Protein

7
New cards

DNA packaging and condensation process?

Topoisomerases - cause the process; there is a nick in a single strand, supercoiling

8
New cards

Goals for replicating the chromosome

Generate 2 identical copies of genetic information; partition in the chromosome so that each daughter cell recieves one