4.13 Drug testing - Withering and modern protocol

Describe how scientists could test whether a salve is an appropriate treatment for humans with wounds infected with S. aureus (4)

-salve must be applied to healthy humans

-treat one group of patients with the salve and another group with an existing treatment

-neither the doctors nor the patients involved in the trial should know which treatment is being used

-participants must be monitored for side effects associated with the salve

-compare the outcomes of patients treated with the salve and the control group

Explain why healthy volunteers were given different doses of the drug or a placebo (3)

-check for side effects

-different doses to determine safe dose

-placebo to make sure any side effects described were due to the drug

Describe how the safe dose of a cancer drug could be determined (3)

-test the drug on healthy individuals

-then test on a group of individuals with cancer

-gradually increasing the dose to determine dose that does not cause side effects

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