MLS Coag/Micro Mock Exam

D. Adhesion, aggregation, plug formation, consolidation, fibrin stabilization

What is the correct sequence of events in hemostatic plug formation?
A. Aggregation, adhesion, plug formation, consolidation, fibrin stabilization
B. Consolidation, aggregation, adhesion, fibrin stabilization, plug formation
C. Adhesion, aggregation consolidation, plug formation, fibrin stabilization
D. Adhesion, aggregation, plug formation, consolidation, fibrin stabilization

B. Glanzmann Thrombasthenia

A 2-year-old child presents with recurrent epistaxis, gum bleeding and occasional hematuria. Upon physical exam, the patient showed petechiae and ecchymoses. The patient is not on any medication.
PT, aPTT, and platelet count are normal. Platelet Function screening tests are abnormal, and a Platelet Aggregation test is ordered. Results are as follows:
Absent/Decreased aggregation with ADP
Absent/Decreased aggregation with Collagen
Absent/Decreased aggregation with Epinephrine
Platelet aggregation was induced (increased within normal range) with Ristocetin
The differential diagnosis should include:
A. Bernard-Soulier
B. Glanzmann Thrombasthenia
C. von Willebrand disease
D. Grey Platelet Syndrome

C. Feedback activation of Factor V and VIII activity

What is the function of thrombin?
A. Convert fibrin to fibrinogen
B. Inactivation of factor XIII
C. Feedback activation of Factor V and VIII activity
D. Activation of fibrinolytic system

A. Platelet count

What laboratory test differentiates primary fibrinogenolysis from DIC?
A. Platelet count
B. PT
C. APTT
D. TT

C. APTT

In early DIC presenting clinically as a hypercoagulable state, it is not unusual for which of the following coagulation times to be paradoxically shortened?
A. Reptilase time
B. Euglobulin lysis time
C. APTT
D. Thrombin time

A. Screens abnormalities in the intrinsic pathway

Match the test with the purpose of the test:
Activated partial thromboplastin time
A. Screens abnormalities in the intrinsic pathway
B. Measures the ability of platelets to inhibit bleeding in vivo
C. In vivo measurement of platelet function
D. Screens abnormalities in the extrinsic pathway

C. Polycythemia vera

Thrombocytosis is characteristic of:
A. Disseminated intravascular coagulation
B. Splenomegaly
C. Polycythemia vera
D. Idiopathic thrombocytopenic purpura

B. PT

An orthopedic patient is placed on low molecular weight heparin after back surgery, in order to determine if the level of LMWH is therapeutic the test to monitored levels would be:
A. Anti-Xa Assay
B. PT
C. Thrombin Time
D. Anti-IIa Assay

B. IX

Hemophilia B is a sex-linked recessive disorder that presents with a decrease in factor:
A. VIII
B. IX
C. X
D. XI

C. 37oC + 1o

Procedures in coagulation are most often performed at what temperature?
A. 4oC +1o
B. 22 oC +5o
C. 37oC + 1o
D. 56oC + 1o

D. LAs/aPLs

Prolongation of the dRRVT test is seen in?
A. Factor I deficiency
B. Factor VII deficiency
C. Protein C deficiency
D. LAs/aPLs

D. Sex-linked recessive

Hemophilia A is a _ disorder that affects approximately one male per 10,000 people in the whole population.
A. Autosomal dominant
B. Autosomal recessive
C. Sex-linked dominant
D. Sex-linked recessive

A. First hour

The principle of clot retraction is based on the premise that with a normal blood specimen, a clot after the _ should retract from the walls of the test tube.
A. First hour
B. Second hour
C. Third hour
D. Fifth hour

D. Serratia marcescens/Escherichia coli

The stock cultures needed for quality control testing of deoxyribonuclease (DNAse) production are:

A. Salmonella typhimurium/Escherichia coli

B. Escherichia coli/Pseudomonas aeruginosa

C. Proteus mirabilis/Escherichia coli

D. Serratia marcescens/Escherichia coli

D. Proteus mirabilis/Escherichia coli

The stock culture needed for quality control testing of deamination activity are:

A. Escherichia coli/Klebsiella pneumoniae

B. Salmonella typhimurium/Escherichia coli

C. Escherichia coli/Pseudomonas aeruginosa

D. Proteus mirabilis/Escherichia coli

C. Escherichia coli/Pseudomonas aeruginosa

The stock cultures needed for quality control testing of oxidase production are:

A. Escherichia coli/Klebsiella pneumoniae

B. Salmonella typhimurium/Escherichia coli

C. Escherichia coli/Pseudomonas aeruginosa

D. Proteus mirabilis/Escherichia coli

D. Klebsiella pneumoniae/Escherichia coli

The stock cultures needed for quality control testing of motility are:

A. Salmonella typhimurium/Escherichia coli

B. Escherichia coli/Pseudomonas aeruginosa

C. Serratia marcescens/Escherichia coli

D. Klebsiella pneumoniae/Escherichia coli