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A. 1.33%
2SD IS GIVEN, THEREFORE 1SD IS 2
CV = (SD/ MEAN) × 100
CV= 2/150 x 100
CV: 1.33%
2. A CHOLESTEROL QUALITY CONTROL CHART HAS THE FOLLOWING DATA FOR THE NORMAL CONTROL:
MEAN of the dta: 150 MG/DL
2SD = 4
N= 10
EX: 1,372 MG/DL
DETERMINE THE COEFFICIENT OF VARIATION FOR THIS CONTROL:
A. 1.33%
B. 2.67%
С. 15.0 %
D. 7.06%7
D. BILIRUBIN 88.4
ARE CORRECT MATCH, EXCEPT:
A. UREA NITROGEN, 0.357
B. TRIGLYCERIDES, 0.01129
C. CHOLESTEROL, 0.02586
D. BILIRUBIN 88.4
INTRALAB (INTERNAL QC)
• INVOLVES ANALYSES OF
CONTROL SAMPLES
TOGETHER WITH PATIENT
SPECIMENS
• DETECTS BOTH RANDOM AND SYSTEMATIC ERRORS
IN A DAILY BASIS
• ALLOWS ID OF ANALYTIC ERRORS WITHIN A ONE-WEEK CYCLE
INTERLAB (EXTERNAL QC)
• INVOLVES PROFICIENCY
TESTING PROGRAMS
• DETERMINES STATE-OF-THE-ART
INTERLABORATORY
PERFORMANCE
COLLEGE OF AMERICAN
PATHOLOGISTS
PROFIENCY PROGRAM - GOLD STANDARD
SYSTEMATIC
Keyword: CONSISTENT
• CALIBRATION PROBLEMS
• CONTAMINATED
SOLUTIONS
• UNSTABLE REAGENT
BLANKS
• LEAKY ISE's
FAILING
INSTRUMENTATION
POORLY WRITTEN
PROCEDURES
RANDOM
• Keyword: VARYING
• Due to: INSTRUMENT, OPERATOR AND ENVIRONMENTAL CONDITIONS:[#11]
• PIPETTING ERRORS
• MISLABELLED
SAMPLES
• TEMPERATURE
FLUCTUATION
A. F TEST
DIFFERENCE BETWEEN THE STANDARD DEVIATIONS OF TWO GROUPS OF DATA
A. F TEST
B. T TEST
C. VARIANCE
D. STANDARD DEVIATION INDEX
F test (SPF)
SD
PRECISION
F TEST
T test (TAM)
T TEST
ACCURACY
MEAN
B. T TEST
IT IS USED TO DETERMINE WHETHER THERE IS STATISTICALLY SIGNIFICANT DIFFERENCE BETWEEN THE MEANS OF TWO GROUPS OF DATA.
A. F TEST
B. T TEST
C. VARIANCE
D. STANDARD DEVIATION INDEX
B. Youden/Twin plot
It is used to compare results obtained on high and low control serum from different laboratories.
A. Gaussian curve (bell-shaped curve)
C. Cumulative sum graph (CUSUM)
B. Youden/Twin plot
D. Shewhart Levey-Jennings chart
A.Tungsten light bulb
It is the most commonly used light source in the visible and near-infrared region:
A.Tungsten light bulb
B. Deuterium lamp
C. Xenon discharge lamp
D. Mercury lamp
B. Diffraction gratings
A monochromator isolates specific wavelength of light. Which of the following is the most commonly used type of monochromator?
A.Prisms
B. Diffraction gratings
C.Filters
D. Prevent excitation light from reaching the detector
36. Fluorometers are designed so that the path of the exciting light is at right angle to the path of the emitted light.
What is the purpose of this design?
A.Prevent loss of emitted light
C. Focus emitted and excitation light upon the detector
B. Prevent loss of the excitation light
D. Prevent excitation light from reaching the detector
Longer wavelength and lower energy
37. A fluorescent substance absorbs light of one wavelength and emits light of:
Longer wavelength and lower energy
Longer wavelength and higher energy
Shorter wavelength and lower energy
Prevent excitation light from reaching the detector
36. Fluorometers are designed so that the path of the exciting light is at right angle to the path of the emitted light.
What is the purpose of this design?
Prevent loss of emitted light
Focus emitted and excitation light upon the detector
Prevent loss of the excitation light
Prevent excitation light from reaching the detector
C. Scintillation counter
39. Which of the following instruments is used in the clinical laboratory or in reference laboratories to detect beta and gamma emissions?
A.Fluorometer
B. Nephelometer
C. Scintillation counter
D. Spectrophotometer
C. Gas chromatography
It is useful for compounds that are naturally volatile or can be easily converted into a volatile form.
A. Paper chromatography
B. Thin layer chromatography C. Gas chromatography
D. HPLC
D. Dialysis
The process used in continuous-flow analysis to separate out protein from the specimen is?
A.Chemical precipitation
B. Column chromatography
C. lon-exchange chromatography
D. Dialysis
A. Batch testing
45. All samples are loaded at the same time and a single test is conducted on each sample:
A. Batch testing
B. Parallel testing
C. Sequential testing
D. Random access testing
C. Sequential testing
Multiple tests analyzed one after another on a given specimen:
A. Batch testing
B. Parallel testing
C. Sequential testing
B. Ostwald-Folin®
Transfer pipet for viscous fluids; it characterized with an etched ring:
A. Volumetric pipet
B. Ostwald-Folin®
C. Serological pipet
D. Mohr pipet
1 2 3 4
Analytes that exhibits diumal variation:
1. Iron
2. Cortisol
3. АСТН
4. GH
500 mg/dL or more
As little as 10% contamination with 5% dextrose will increase glucose in a blood sample by mg/dL or more.
Order of draw from CATHETER LINES:
First 3 to 5 ml blood is
discarded THEN, blood culture, anticoagulated tubes and clot tubes.
Decreased LD and LD5, increased ALP
Low temperature storage prior to testing:
АСТН
Catecholamines
Cortisol
Hormones that tend to increase glucose concentration:
1, 2, and 3
Laboratory findings in hyperglycemia:
1. Increased glucose in plasma and unne
2. Increased urine specific gravity
3. Presence of ketones in serum and urine
4. Increased blood pH and urine pH
7 mg/dL lower
Venous blood is
than capillary blood due to tissue metabolism.
1 2 3
Alkaline copper reduction method for glucose:
1 Folin Wu method
2. Nelson Somogyi method
3. Neocuproine method
D 1, 2, 3 and 4
Diagnostic criteria for diabetes mellitus:
A. RBS ≥ 200 mg/dL
2. FBS ≥ 126 mg/dL
3. 2-hour post glucose load ≥ 200 mg/dL
A. 1 and 2
B. 1 and 3
C. 1,2 and 3
D 1, 2, 3 and 4
D. 1, 2, 3 and 4
Methods for measurement of glycosylated hemoglobin (HbA1c):
Electrophoresis
HPLC
Affinity chromatography
Immunoassay
A. 1 and 3
B. 2 and 4
C. 1, 2 and 3
D. 1, 2, 3 and 4
30% phospholipid, 20% chole ester + 45-50% protein
Low density lipoprotein:
90% TAG + 1-2% protein
65% TAG, 16% chole ester + 6-10% protein
30% phospholipid, 20% chole ester + 45-50% protein
50% chole ester + 18% protein and phospholipid
Tangier's disease
A rare autosomal recessive disorder characterized by complete absence of HDL:
Bassen-Korzweig syndrome
Tangier's disease
Anderns dies
LpX
An abnormal lipoprotein found in patients with obstructive biliary disease: