Clin Path - RBC Morphology

what is a poikilocyte

variation in shape

Schistocyte

RBC fragment

- associated with DIC

Acanthocyte

- Uneven projections on membrane (Spurr cell)

- liver disease

Echinocyte

- even projections on membrane (burr cell)

- human error

Keratocyte

- blister cell

- liver issues, BM issue, 2nd to anemia

spherocyte

- only in dogs

- auto immune disease

Types of Leptocytes

- Condocyte (target cell)

- Stomatocytes,

- Knizocyte (Bar cell)

Target cell

condocyte

stomatocyte

barr cell

knizocyte

elliptocyte

- ovalocyte

- liver/kidney disease

eccentrocyte

diabetes/cancer/toxins

dacryocyte

- tear shape

- BM issues

- human error

Basophillic Stippling

- dark speckles

- rumintants/cats with anemia

Howell-Jolly Bodies

- nuclear remnants

- anemia

Heinz Bodies

- pale area

- cancer/hyperthyroidism/diabetes

Mycoplasma haemofelis

- found on membrane

- may trigger immune response

bone marrow not working & non regenerative appearance

- Normocytic

- normochromic

- low PCV

BM responding, regenerative, has reticulocytes

- macrocystic

- polychromic

iron deficiency appearance

- microcytic

- hypochromic

what is macrocytic, normochromic cells

- rare

- caused by genetics, FeLV, B12 deficiency