Intracellular Signaling After Hormone Receptor Activation

Flashcards covering key vocabulary related to intracellular signaling after hormone receptor activation.

G Protein-Linked Hormone Receptors

Receptors that activate G proteins to trigger intracellular signaling pathways.

Enzyme-Linked Hormone Receptors

Receptors that directly activate enzymes upon hormone binding.

Second Messenger Systems

Intracellular signaling mechanisms activated by hormones, like cAMP and phospholipase C pathways.

Adenylyl Cyclase

An enzyme that converts ATP to cAMP, a second messenger involved in signal transduction.

cAMP

Cyclic adenosine monophosphate, a second messenger that activates protein kinases.

Phospholipase C

An enzyme that generates second messengers DAG and IP3 from phospholipids.

Lipid-soluble Hormones

Hormones that can diffuse through the plasma membrane and bind to intracellular receptors.

JAK2

A kinase involved in the signaling of various hormone receptors, including leptin receptors.

STAT3

A transcription factor activated by cytokine receptors associated with JAK2.

Radioimmunoassay (RIA)

A technique to measure hormone concentrations in blood using radioactively labeled antibodies.

Enzyme-Linked Immunosorbent Assay (ELISA)

A common laboratory technique to detect and quantify hormones in samples.