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SAD
- marked fear about social situations
- exposure to feared circumstance --> panic attacks
SAD: Clinical Presentation
- fears: scrutiny by others, negatively evaluated
- physical: blushing, diarrhea, stumbling over words, sweating, tachycardia, trembling
- specifier: performance (fear of public speaking)
SAD: DSM-5 Criteria
- intense, irrational & persistent fear of being scrutinized in at least one social or performance situation
- exposure to fear initiates attack
- blushing is the principal physical indicator
- recognize fear is excessive & unreasonable, but unable to overcome w/o tx
SAD: Goals of Therapy
- acute phase: reduce sx of anxiety, social anxiety, & phobic avoidance
- continuation phase: extend therapeutic benefits, reduce sx, improve QoL
- maintenance: maintain improvement, decr rate of relapse
SAD: Non-pharm Therapy
- support groups
- CBT: exposure therapy, social skills training, relaxing training techniques
Pharmacologic Tx 1st line
- SSRIs
- venlafaxine XR
Pharmacologic Tx 2nd line
- clonazepam
- buspirone
Pharmacologic Alternatives
- gabapentin
- phenelzine
- pregabalin
First Line Agents
- paroxetine (prevents relapse)
- sertraline (FDA approved for long-term use)
- escitalopram (prevents relapse)
- fluvoxamine ER
- venlafaxine ER (prevents relapse)
>> similar doses as in depression
>> improve anxiety & avoidance sx
SAD Treatment Algorithm
- SAD --> SSRI or venlafaxine XR for 12 wks
- response = continue for 6-12 mo
- no response = switch to diff SSRI or venlafaxine XR
- partial response: consider augmentation w/ buspirone or clonazepam

SAD Alternatives
- clonazepam: improves fear & phobic avoidance, interpersonal sensitivity
- B-blockers: for performance-related situations, decr perception of anxiety (propranolol, atenolol)
>> take 1-2 hrs b4 performance
Key Points
- SAD = intense, irrational, persistent fear of being negatively evaluated or scrutinized
- SSRIs/SNRIs are 1st line
- B-blockers should be used for performance anxiety