Biochemistry - Chapter 18 - Pyruvate Dehydrogenase
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5 Terms
What is the reaction of an irreversible link between glycolysis and citric acid cycle?
Oxidative decarboxylation of pyruvate and the sequence of reactions in the citric acid cylce take place where?
…within the matrix.
Acetyl CoA has two principle fates:
Metabolism by the citric acid cycle
Incorporation into fatty acids
What are the two self-inhibition of the pyruvate dehydrogenase (PDH) complex is regulated to respond to the energy charge of the cell?
The complex is inhibited by its immediate products, NADH and acetyl CoA, as well as by the ultimate product of cellular respiration, ATP.
(A)The complex is activated by pyruvate and ADP, which inhibit the kinase that phosphorylates PDH.
Know the pathway
Note 
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