Chapter 3. Histology

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84 Terms

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What is histology?

The study of body tissue

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What is cell differentiation?

It’s the developmental process that results in the formation of different (specialized) types of cells.

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What are the four types of tissue in the body?

Epithelial, connective, muscle, nerve

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What are the 3 general characteristics of epithelial tissue?

  1. The epithelial cells adhere (stick) close together

  2. The epithelial tissues contain no blood vessels (avascular)

  3. They’re often found covering a body surface/lining body cavities

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What does avascular mean?

without blood vessels

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What are 3 ways epithelial tissue are classified?

  1. layers

  2. shape

  3. modifications

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What are simple cells?

They are cells with 1 layer

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What are stratified cells?

They are cells with multiple layers

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How do squamous cells look?

flat

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How do cuboidal cells look?

boxy

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How do columnar cells look?

Long, like a column

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What are the 3 cellular modifications?

  1. cillia

  2. microvilli

  3. goblet cells

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What types of cells do you find cellular modifications on?

columnar epithelial cells

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What are cillia?

They are fine motile hairs

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What are microvilli?

They are finger-like extensions of the cell AKA brush border

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What are goblet cells?

They are mucous secreting cells.

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Where do you find simple squamous epithelial cells?

in the alveoli, the lining of blood vessels, and within various membranes of the body.

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Where are simple cuboidal cells found?

the urinary tubules of the kidney, the lives, pancreas, thyroid and other glands of the body.

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What does Aden/o mean?

gland

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Where do you find simple columnar cilitated epithelial cells?

In the fallopian tubes (oviducts)

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What do cillia on the fallopian tubes do?

They carry eggs up to the ovaries

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Where do you find simple columnar epithelium with goblet cells ?

in the stomach

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What do goblet cells in your stomach do?

neutralize stomach acid

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Where do you find simple columnar brush border epithelium with goblet cells?

In the lining of the intestine

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Where do you find pseudostratified columnar ciliated epithelium with goblet cells

in the lining of the respiratory tract

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What does pseudo mean?

false

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What does pseudostratified mean?

false layers

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What does cilia on the respiratory tract do?

catch dust

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Where do you find transitional epithelium

in the lining of the urinary bladder

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Why is it called transitional epithelium?

The tissue changes/transforms, because it stretches as the bladder fills with urine.

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What does lumen mean?

whole

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What are the 2 subtypes of stratified squamous epithelium?

Non keratinizing and keratinizing

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What is Keratin?

dead layers of cells

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Where do you find keratin

In your skin, nails, and hair

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What are non-keratinizing stratified squamous epithelium?

They are non-dead layers of cells

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Where do you find non-keratinizing stratified squamous epithelium?

in the oral cavity, anal canal, and vaginal canal

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What is keratinizing stratified squamous epithelium?

dead layers of cells

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Where do you find keratinizing stratified squamous epithelium?

in the epidermis of the skin

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What do all cells need to be surrounded by?

fluid

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What is the function of connective tissue?

to connect and support the other tissues of the body

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How are connective tissue classified?

They are classified based on the type of cell and the type of intercellular matter between the cells

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What is areolar loose connective tissue?

They are fibroblasts, macrophages, and mast cells.

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What are fibroblasts?

They are a principal type of cell that secrete proteins into the space between cells.

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What are macrophages?

They engulf foreign agents such as cells

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What are mast cells?

They are cells that secrete histamine and other chemical mediators of inflammation

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What is inflammation?

It refers to the local dilation of blood vessels (erythema), local increase in the permeability of blood vessels (causes edema), and the local stimulation of pain fibers (causes pain)

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What does erythema mean?

Turning red

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What is edema?

swelling

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What are 2 proteins secreted by fibroblasts?

collagen and elastin

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What is collagen?

protein fibers that strengthen the tissue

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What is elastin?

protein fibers that bring elasticity to the tissue

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What is adipose tissue?

It refers to tissue made of cells with closely packed adipose (fat) cells

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What is the function of adipose tissue?

Adipose tissues provides a reserve of food (for energy), insulate against heat loss, support & protects the organs it encloses

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What are three common locations of adipose tissue

Under the skin (subcutaneous fat), around the kidneys and eyeballs, and around the buttocks and breasts

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What are the two subtypes of dense fibrous connective tissue?

The regularly arranged dense fibrous tissue and the irregularly arranged dense fibrous tissue.

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What are five places where dense fibrous connective tissue is common?

tendons (muscles to bones), ligaments (cords that connect bones together), fascia (encloses muscles), perichondrium & periosteum (cartilage and bones)

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What does peri mean?

around

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How do regularly arranged fibrous connective tissue look?

The protein fibers are arranged in parallel bundles

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How do irregularly arranged dense fibrous connective tissue look?

The protein fibers are interwoven, running in all directions

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What is special about cartilage tissue, unlike other connective tissue?

it has no blood vessels (non-vascular) which is an exception to other connective tissues

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What are the three subtypes of cartilage?

Hyaline, Fibrocartilage, and elastic cartilage

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What are 4 locations where hyaline cartilage is found?

The embryonic long bones of the body, the front of the nose, the trachea & larynx, and the surfaces of articulating bones.

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Where is elastic cartilage found?

The external ear (pinna)

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Where is fibrocartilage found?

In the intervertebral disks

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What are osteocytes?

They are a bone cell surrounded by a pocket of fluid

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What does a compact bone look like?

The osteocytes are arranged in concentric circles known as haversian systems (osteons).

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What does a spongy bone look like?

The osteocytes are arranged in a spongy network

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What are osteoblasts?

They are cells that secrete calcium minerals and form bone tissue

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What are osteoclasts?

cells that break-down calcium mineral

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What is resorption?

the breakdown of calcium mineral

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What is ossification?

the formation of bone tissue

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What are the haversian systems

The arrangement of osteocytes in concentric circles, also known as osteons

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What is a diaphysis?

the shaft of the bone

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What is an epiphysis?

The wide end of bone, that can be separated from the diaphysis by the epiphyseal plates

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What is the medullary cavity?

It is a cavity in the bones that contains red marrow

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What is hemopoiesis?

hemopoiesis means to create blood

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What is hemopoietic tissue?

It includes blood and lymph. Red blood cells, white blood cells, and blood platelets are included.

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What are erythrocytes?

They are red blood cells which are responsible for transporting O2 and CO2

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What are leukocytes?

They’re white blood cells that produce antibodies and interferon that inactivate foreign agents.Phagocytes are a type of leukocyte that engulf foreign agents.

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What are platelets?

They are cell fragments that produce thromboplastin which triggers blood clotting

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What are neoplasms?

They are tumors

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What are benign tumors?

They are harmless tumors

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What are malignant tumors

They are cancerous tumors

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What is thromboplastin?

They are a substance that triggers blood clotting