Immuno Exam 2 - Memory Chapter 10

what kind of cells are adaptive memory cells?

B cells, T helper cells and T killer cells

when B cells are activated (initial invader), 3 kinds of B cells are made:

short-lived plasma cells, long-lived plasma cell (memory), central memory B cell

what are short-lived plasma cells produced in ?

lymphoid follicles of secondary lymphoid organs

short lived plasma cells travel to what structures?

bone marrow and spleen

short-lived plasma cells produce a ton of what?

antibodies

how long do short-lived plasma cells live?

few days

what are long-lived plasma cells produced in?

lymphoid follicles of secondary lymphoid organs

long lived plasma cells produce modest amounts of what?

antibodies

long-lived plasma cells provide what?

life-long Ab protection

what type of cell replace long-lived plasma cells which die from old age and quickly proliferate if we encounter an invader again, making more short-lived plasma B cells?

central memory B cells (memory stem cells)

how does B cell memory relate to primary and secondary antibody responses?

secondary response allows for a faster response and more specific Ab to be made for specific pathogen, because memory cells have already seen a particular pathogen in primary response

what type of T cell travels to battle site and fights?

effector T cell

what type of T cell travels to battle site and remain for up to 10 years?

memory effector T cells

what type of T cell starts in secondary lymphoid organs and bone marrow?

central memory T cells

how do memory B cells help with a more robust response?

more cells specific to invader, memory B and T cells easier to activate, memory B cells are upgraded

how are memory B cells upgraded to allow a robust defense?

somatic hypermutation create a better fit to invader

what type of memory is static and is essentially the same in all humans?

innate

what type of memory is expandable, remembers any invader they met and is unique in each human depending on invaders its encountered

adaptive