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Last updated 1:10 AM on 3/27/26
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77 Terms

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Glycolysis

The metabolic pathway that breaks down glucose into pyruvate, producing a small amount of ATP and NADH.

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Intermediate stage

The process of converting pyruvate into acetyl-CoA in the mitochondria, linking glycolysis to the citric acid cycle.

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Citric acid cycle

A series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats, and proteins.

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Electron transport chain

A series of protein complexes in the inner mitochondrial membrane that produces the majority of ATP in cellular respiration using oxygen.

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Substrate-level phosphorylation

The direct production of ATP from a substrate during glycolysis and the citric acid cycle.

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Oxidative phosphorylation

The indirect production of ATP, utilizing electron carriers NADH and FADH₂ in the electron transport chain.

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Acetyl-CoA

A crucial molecule in cellular respiration formed from pyruvate, it serves as the entry point into the citric acid cycle.

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Pyruvate

The end product of glycolysis, a 3-carbon molecule that can be converted into lactate under anaerobic conditions.

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Pyruvate dehydrogenase

An enzyme that converts pyruvate into acetyl-CoA during the intermediate stage of respiration.

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Fatty acids

Long-chain hydrocarbons that are oxidized to acetyl-CoA, entering the citric acid cycle for ATP production.

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Amino acids

Building blocks of proteins that can be deaminated and enter cellular respiration at different points after removal of the nitrogen group.

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NAD⁺

A coenzyme that accepts electrons and becomes NADH, which is usable in the electron transport chain.

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NADH

The reduced form of NAD⁺ that carries electrons to the electron transport chain, playing a key role in ATP production.

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Citrate

The first molecule formed in the citric acid cycle, created by the combination of acetyl-CoA and oxaloacetate.

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Oxaloacetate

A four-carbon molecule that combines with acetyl-CoA to form citrate in the citric acid cycle.

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ATP

A high-energy molecule produced in cellular respiration, which serves as the main energy currency of the cell.

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ADP

A low-energy molecule that, when phosphorylated, converts to ATP, thus storing energy.

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Allosteric inhibition

Regulation of enzyme activity by binding of a molecule at a site other than the enzyme's active site, like ATP inhibiting PFK in glycolysis.

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Metabolic pathways

A series of linked biochemical reactions catalyzed by enzymes, resulting in the conversion of substrates into products.

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Pyruvate → lactate

The conversion of pyruvate to lactate under anaerobic conditions, which regenerates NAD⁺.

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Carbon skeleton of amino acids

The remaining structure of an amino acid after deamination, which can enter various pathways for energy production.

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Cristae

The folds of the inner mitochondrial membrane where the electron transport chain occurs.

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Hydrogen gradient

The difference in hydrogen ion concentration across a membrane, used by ATP synthase to synthesize ATP.

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Glycolysis control point

Phosphofructokinase (PFK) inhibited by ATP, controlling the flow through glycolysis.

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Lacteals

Lymphatic vessels in the intestines that absorb and transport lipids into the lymphatic system.

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Cholecystokinin (CCK)

A hormone that stimulates gallbladder contraction to release bile and pancreatic enzyme secretion.

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Insulin

A hormone released when blood glucose is high; it promotes glucose uptake into cells and glycogen storage.

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Glucagon

A hormone secreted when blood glucose is low; it promotes the conversion of glycogen to glucose.

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Gastrin

A hormone that increases gastric acid secretion and motility in response to food in the stomach.

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Bile

A digestive fluid produced by the liver that emulsifies fats, aiding in their digestion and absorption.

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Pepsinogen

An inactive precursor of pepsin, activated by hydrochloric acid in the stomach for protein digestion.

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Amino acid deamination

The removal of an amino group from an amino acid, allowing the remaining carbon skeleton to enter metabolic pathways.

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Proteins

Macromolecules made of amino acids that serve various functions including structural, enzymatic, and regulatory roles.

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Liver function

The production of bile, synthesis of proteins, and detoxification of metabolites.

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Small intestine

The primary site of digestion and absorption of nutrients in the digestive tract.

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Mucosa

The innermost layer of the GI tract wall, involved in secretion and absorption.

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Serosa

The outermost layer of the GI tract wall, providing protection and supporting structure.

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Peristalsis

The coordinated contraction and relaxation of smooth muscles in the GI tract to move contents forward.

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Segmentation

A localized contraction of intestinal muscles that mixes food and increases absorption.

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Nutrient absorption pathways

The process whereby absorbed nutrients enter circulation, with most nutrients going into blood and fats entering lymph.

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Fats

Lipids composed of fatty acids and glycerol, serving as long-term energy sources and insulation.

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Glucose

A simple sugar that is a primary energy source for cells and enters glycolysis during cellular respiration.

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Fructose

A simple sugar found in fruits; it can be metabolized into glucose or used directly for energy.

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Sucrose

A disaccharide composed of glucose and fructose, which can be broken down into its components.

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Lipoproteins

Complexes of lipids and proteins that serve to transport lipids in the blood.

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Glycogen

The stored form of glucose in animals, primarily found in the liver and muscles.

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Carbohydrate digestion

The process of breaking down carbohydrates into glucose, which can then be utilized for energy or stored.

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Fat digestion

The emulsification of fats by bile followed by the breakdown by lipase in the small intestine.

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Protein digestion

The breakdown of proteins into amino acids through the action of enzymes like pepsin and proteases.

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Chymotrypsin

An enzyme produced by the pancreas that digests proteins into peptides.

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Trypsin

A protease enzyme produced in the pancreas that helps to break down proteins in the small intestine.

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Fiber

A type of carbohydrate that is not digestible and aids in intestinal movement.

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Minerals

Inorganic substances required for various physiological functions, such as calcium for bones and iron for oxygen transport.

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Vitamins

Organic compounds that are essential for various metabolic processes in the body, divided into water-soluble and fat-soluble categories.

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Essential nutrients

Nutrients that must be obtained from dietary sources because the body cannot synthesize them.

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Non-essential nutrients

Nutrients that can be synthesized by the body and do not need to be obtained through diet.

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Continuous muscular tube

Describes the structure of the GI tract, functioning in sequential segments for digestion and absorption.

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Hydrochloric acid (HCl)

An acid produced in the stomach that aids in digestion by activating pepsin and denaturing proteins.

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Motility

The ability of the digestive system to move food through peristalsis and segmentation.

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Energy balance

The relationship between energy intake from food and energy expenditure from metabolic processes.

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Absorption process

The uptake of nutrients from the digestive tract into the bloodstream or lymphatic system.

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Fluid balance

The maintenance of the proper amount and distribution of water and electrolytes in the body.

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Caloric intake

The number of calories consumed through food and beverages.

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Caloric expenditure

The number of calories burned through metabolic processes and physical activity.

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Nutritional balance

Achieving appropriate levels of macronutrients and micronutrients for overall health.

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Sphincter muscles

Muscle rings that control the passage of food through the digestive tract.

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Digestive enzymes

Biological molecules that speed up the digestion of food into absorbable units.

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Hydration

The process of absorbing water necessary for various physiological functions.

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Nutrient requirements

The specific amount of each nutrient that individuals need for optimal health.

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Polyunsaturated fats

Fats that contain more than one double bond in their fatty acid chains and are beneficial for heart health.

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Saturated fats

Fats that are solid at room temperature and can raise cholesterol levels if consumed in excess.

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Dietary fiber

Parts of plant-based foods that cannot be digested, helping to regulate the body's use of sugars.

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Unsaturated fats

Fats that are liquid at room temperature and are generally healthier than saturated fats.

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Complete proteins

Proteins that contain all essential amino acids needed by the body.

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Incomplete proteins

Proteins that lack one or more essential amino acids.

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Nutritional deficiencies

Health problems resulting from inadequate intake or absorption of essential nutrients.

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Therapeutic diet

Diets specifically designed to treat or manage health conditions.

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