ap 2 exam 3
A & P 2 – EXAM 3 (1 APRIL 2026)
CHAPTER 3 — CELLULAR RESPIRATION
1. Know about Glycolysis, intermediate stage, citric acid cycle and electron transport chain
Glycolysis:
• Occurs: cytosol
• Anaerobic (does not require oxygen)
• Breaks glucose into pyruvate
• Produces a small amount of ATP.
• SUBSTRATE: Starting molecule (substrate) = glucose
• PRODUCT = pyruvate
• ATP: 2 net ATP produced
• CO-ENZYME PRODUCED = NADH
Intermediate stage:
• Converts pyruvate into acetyl-CoA in the mitochondria
• Links glycolysis to the citric acid cycle.
• SUBSTRATE: Starting molecule (substrate) = pyruvate
• PRODUCT = acetyl-CoA + CO₂
• ATP: 0 ATP produced
• CO-ENZYME PRODUCED = NADH
Citric acid cycle:
• Occurs in the mitochondrial matrix
• Generates electron carriers (NADH and FADH₂)
• Generates small ATP.
• SUBSTRATE: Starting molecule (substrate) = acetyl-CoA
• PRODUCT = CO₂
• ATP: 2 ATP total
• CO-ENZYME produced = NADH and FADH₂
The electron transport chain:
• Occurs in the cristae (inner mitochondrial membrane)
• Produces most ATP using oxygen (aerobic).
• Regenerates NAD+ so glycolysis can continue
• SUBSTRATE: Starting molecule (substrate) = NADH, FADH₂, oxygen
• PRODUCT = water
• ATP: Most ATP – major source
• CO-ENZYME produced = uses NADH and FADH₂
2. Know about substrate-level phosphorylation
• This is direct ATP production from a substrate.
• Occurs in glycolysis and the citric acid cycle
• Produces small amounts of ATP.
3. Know about oxidative phosphorylation
• This is indirect ATP production using NADH and FADH₂
• Occurs in the electron transport chain.
• Produces most ATP.
4. Know about acetyl-CoA
• Acetyl-CoA is formed from pyruvate and is the entry molecule into the citric acid cycle.
• It connects carbohydrate, fat, and protein metabolism.
5. Describe what happens to pyruvate with insufficient oxygen
• If oxygen is low, pyruvate is converted into lactate.
• This genenrates NAD+ so glycolysis can continue
6 Know pyruvate dehydrogenase
• This enzyme converts pyruvate into acetyl-CoA in the intermediate stage. It is a key control step.
6. Know what pyruvate is (not a enzyme but a molecule)
• Pyruvate is the end product of glycolysis.
• It is a 3-carbon molecule that either enters the mitochondria or becomes lactate.
7. Describe how other fuel molecules like fatty acids and amino acids are utilized to make ATP
• Fatty acids are broken down into acetyl-CoA and enter the citric acid cycle.
• Amino acids are deaminated (nitrogen removed), and their carbon skeleton enters cellular respiration at different points.
• All fuels ultimately feed into the pathway to produce ATP.
🚨 DIRECTLY MENTIONED = EXPECT QUESTIONS
1. Acetyl-CoA
👉 She literally said:
“you’re going to have a test question about acetyl-CoA”
Know:
Formed from pyruvate + CoA (via pyruvate dehydrogenase)
Happens in mitochondria
Required to enter Citric acid cycle
2. Oxaloacetate
👉 She said:
“you’ll have a question on oxaloacetate”
Know:
Combines with acetyl-CoA
Forms citrate
3. Citrate
👉 She tied this directly to the above
Know:
First molecule in Citric acid cycle
Formed from: 👉 acetyl-CoA + oxaloacetate
🚨 HEAVILY EMPHASIZED (WILL BE TESTED INDIRECTLY)
🔥 4. Metabolic pathways + enzymes
She OPENED with this → very important
Know:
Product → becomes next substrate
Multi-enzyme chain
Negative feedback regulation
👉 End product (ATP) shuts pathway off
🔥 5. Allosteric inhibition (PFK)
She repeated this multiple times
Know:
ATP binds enzyme → changes shape
Shuts down glycolysis
👉 This is a classic trick question
🔥 6. ATP vs ADP
She slowed down here → important
Know:
ADP + phosphate → ATP (phosphorylation)
ATP → ADP (dephosphorylation)
👉 reversible
🔥 7. Substrate vs Oxidative phosphorylation
She clearly contrasted these
Know:
Substrate-level = direct (low ATP)
Oxidative = indirect via NADH/FADH₂ (HIGH ATP)
👉 She emphasized: indirect = most ATP
🔥 8. NAD⁺ / NADH
She spent time explaining this
Know:
NAD⁺ = accepts electrons
NADH = carries electrons
Feeds into ETC
👉 Required for ATP production
🔥 9. Glycolysis basics (but focus on control)
She did NOT want steps memorized
Know:
Occurs in cytosol
No oxygen required
2 ATP invested
👉 Control point:
PFK inhibited by ATP
🔥 10. Fate of pyruvate (VERY IMPORTANT)
She used exercise example → big signal
With oxygen:
→ acetyl-CoA → Krebs
Without oxygen:
→ lactate
👉 WHY:
Regenerate NAD⁺
👉 She tied this to:
Muscle soreness
🔥 11. Intermediate stage
She simplified it
Know:
Pyruvate → acetyl-CoA
Produces NADH
Happens twice per glucose
🔥 12. Citric acid cycle(what she cares about)
She said: 👉 don’t memorize steps
👉 focus on key parts
Know:
Location: matrix
Produces:
NADH
FADH₂
ATP
CO₂
👉 Regulation:
Citrate synthase
Controlled by ATP levels
🔥 13. Energy demand regulation
She clearly explained this
High energy demand → ↑ cycle activity
Low energy demand → ↓ cycle activity
👉 ties to ATP levels
🔥 14. Electron Transport Chain (VERY HIGH-YIELD)
She emphasized HARD:
Know:
Location: cristae
Uses:
NADH
FADH₂
🔥 Core mechanism:
Hydrogen pumps
Create gradient
ATP synthase makes ATP
🔥 Oxygen:
👉 final electron acceptor
👉 forms water
🚨 If ETC stops:
No NAD⁺ regeneration
Glycolysis stops
ATP collapses
👉 She explicitly walked through this
🔥 15. ATP Synthase
She highlighted:
👉 builds ATP
👉 uses proton gradient
🔥 16. Fat + protein entry into pathway
She mentioned near the end
Know:
Fats → acetyl-CoA
Proteins → enter at different points
Nitrogen → urea
🚨 VERY HIGH-YIELD SUMMARY (what to memorize cold)
If you ONLY know this, you’re in a strong position:
Acetyl-CoA, oxaloacetate, citrate
ATP inhibits glycolysis (PFK)
NAD⁺ / NADH role
Pyruvate → lactate (no O₂)
ETC = H⁺ gradient + ATP synthase
Oxygen = final electron acceptor
Substrate vs oxidative phosphorylation
Fats/proteins enter pathway
CHAPTER 26 — DIGESTIVE SYSTEM
1. Know organs of the GI tract
• Mouth
• Pharynx
• Esophagus
• Stomach
• Small intestine (duodenum, jejunum, ileum)
• Large intestine
2. Know accessory digestive organs
• Salivary glands (submandibular, sublingual, parotid)
• Liver
• Gallbladder
• Pancreas
3. Know the function of the GI tract
• To break down food into absorbable molecules and move them through the body.
4. Know the function of digestive organs
• Each organ contributes to digestion, absorption, movement, or secretion.
5. Know the stages and functions of the phases of digestion
• Cephalic phase: brain prepares digestion
• Gastric phase: stomach digestion
• Intestinal phase: small intestine digestion and absorption
6. Tunics of the GI wall
• Mucosa (innermost)
• Submucosa
• Muscularis externa
• Serosa (outermost)
8. Describe regulation of the digestive system (ENS, ANS and hormones!)
Systems:
• Enteric nervous system (ENS) – controls digestion locally.
• Autonomic nervous system (ANS) – modifies digestion (parasympathetic increases, sympathetic decreases).
Hormones:
• Gastrin increases secretion (acid) and motility
• Cholecystokinin (CCK) releases bile and pancreatic enzymes
9. Describe serous membranes of the GI tract
They reduce friction and cover organs.
• Visceral peritoneum (innermost)
• Parietal peritoneum (outermost)
10. Describe intraperitoneal organs
• Organs fully surrounded by peritoneum (serous membrane of the GI tract) and suspended by mesentery (organ that anchors intestines to abdominal wall, supplies blood, nerves and houses lymph nodes)
11. Describe retroperitoneal organs
• Organs behind the peritoneum, not fully covered.
12. Individual mesenteries of the abdominopelvic cavity
• They anchor organs and carry blood vessels and nerves.
13. Describe each of the components of the GI tract
• Oral cavity → ingestion, mechanical breakdown, salivary enzymes
• Pharynx → passageway, swallowing
• Esophagus → peristalsis → moves bolus
• Stomach → storage, mixing, protein digestion → chyme
• Small intestine → digestion + major absorption in duodenum
• Large intestine → water and electrolyte absorption, feces formation
14. Describe the anatomy of the GI tract
• Continuous muscular tube from mouth → anus
Layers (tunics 4):
• Mucosa (innermost)
• Submucosa
• Muscularis externa
• Serosa/adventitia (outermost)
Specialized structures:
• Stomach folds (rugae)
• Small intestine → villi + microvilli (these increase surface area and therefore absorption)
15. Describe the histology of the GI tract
Mucosa:
• Epithelium → absorption/secretion
• Lamina propria → connective tissue with blood and lymph vessels
• Muscularis mucosae → smooth muscle for local movement
Submucosa:
• Blood vessels, nerves and glands
Muscularis externa:
• Circular layer → mixing
• Longitudinal layer → movement
Serosa:
• Outer covering
👉 Key idea:
Structure supports digestion + absorption
16. Describe the processes of the GI tract
Ingestion:
• Taking food into the mouth
Motility = movement of food:
• Peristalsis – moving food forward
• Segmentation – mixing
Secretion:
• Release of enzymes
• Release of acid
• Release of bile
• Release of hormones
Digestion = breaking down of food:
• Mechanical (chewing, churning)
• Chemical (enzymes)
Absorption:
• Nutrients enter blood
• Fats enter lymph (lacteals)
Elimination
• Waste removal (feces)
17. Describe the secretions of the GI tract
Saliva:
• Amylase (enzyme that breaks down starch)
• Lingual lipase (enzyme that breaks down lipids)
Stomach cells in the gastric pits:
Parietal cells
• Secrete hydrochloric acid (HCl)
• Secrete intrinsic factor
Chief cells
• Secrete pepsinogen → becomes pepsin (protein digestion)
Mucous cells
• Secrete mucus → protects stomach lining from acid
G cells
• Secrete gastrin (hormone) → increases: acid secretion and motility
Pancreas:
• Releases emzymes like amylase, lipase, proteases
• Bicarbonate (neutralizes acid)
Liver:
• Bile (fat emulsification)
Small intestine:
• Enzymes
• Hormones such as secretin which is released from the duodenum and stimulates the pancreas to release bicarbonate. CCK is also released from the duodenum and contracts gallbladder for bile release, and stimulates pancreas for enzyme secretion
18. Describe the functions of the GI tract
Break down food into absorbable molecules (catabolism)
Absorb nutrients into:
• Blood (most nutrients)
• Lymph (fats)
Maintain fluid balance
Eliminate waste
👉 Core purpose: Food → small molecules → absorption → energy (ATP)
19. Describe the regulation for the oral cavity
• Voluntary control (you choose to eat)
• Salivation reflex: triggered by sight, smell, taste
• Controlled by ANS: parasympathetic nervous system which increases saliva because digestion gets “turned on”
20. Describe the regulation for the salivary glands
• Controlled by ANS
• Parasympathetic (rest and digest) → watery saliva
• Sympathetic (flight or flight) → thicker saliva
Triggered by:
• Food presence
• Sensory input
21. Describe the regulation for the pharynx (throat)
• Controlled by swallowing reflex
• Involuntary phase
• Regulated by the Medulla (brainstem)
• Ensures epiglottis closes airway
• Food directed to esophagus
22. Describe the regulation for the esophagus
• Controlled by peristalsis (reflex)
• Upper esophageal sphincter → voluntary start
• Lower esophageal sphincter: relaxes → allows food into stomach
• Controlled by ANS + ENS
23. Describe the regulation for the stomach
• Controlled by ANS (parasympathetic increases activity)
Hormones: (gastrin)
• Increases HCl secretion
• Increases motility
Triggered by:
• Food in stomach
• Baroreceptors (stretching)
24. Describe each of the components of the lower GI tract
• Small intestine → digestion + absorption
• Liver → produces bile
• Gallbladder → stores/releases bile
• Pancreas → enzymes + bicarbonate
• Large intestine → water and electrolyte absorption, feces
25. Describe the anatomy of the lower GI tract
Small intestine:
• Duodenum, jejunum, ileum
• Villi + microvilli
Liver:
• Largest organ, produces bile
Gallbladder:
• Small sac under liver
Pancreas:
• Behind stomach
Large intestine:
• Cecum → colon → rectum
26. Describe the processes of the lower GI tract
Small intestine:
• Digestion + absorption
Liver:
• Bile production
Gallbladder:
• Bile release and storage
Pancreas:
• Enzyme secretion
Large intestine:
• Water and electrolyte absorption
• Feces formation
27. Describe the secretions of the lower GI tract
• Small intestine → digestive enzymes, hormones
• Liver → bile
• Gallbladder → releases and stores bile
Pancreas:
• Amylase (starch/carbs)
• Lipase (fats)
• Proteases (proteins)
• Bicarbonate
28. Describe the functions of the lower GI tract
• Complete digestion
• Absorb nutrients
• Absorb water
• Form and eliminate feces
• Emulsify fats via bile
29. Describe the regulation for the small intestine
Controlled by:
• ENS (local control)
• ANS
Hormones (CCK)
• Released from duodenum
• Stimulates gallbladder contraction
• Stimulates pancreatic enzyme release
30. Describe the regulation for the liver
Regulated indirectly by hormones:
• CCK (bile release via gallbladder)
Also regulated by:
• Nutrient levels in blood
31. Describe the regulation for the gallbladder
Controlled by CCK
CCK causes:
• Contraction → bile release
32. Describe the regulation for the pancreas
Controlled by:
• CCK → enzyme release
• Secretin → bicarbonate release
Triggered by:
• Chyme entering duodenum
33. Describe the regulation for the large intestine
Controlled by:
• ENS (local reflexes)
• ANS
Functions regulated:
• Water and electrolyte absorption
• Defecation reflex
34. Describe the major classes of macromolecules
• Carbohydrates → sugars/starches → main energy source
• Proteins → amino acids → structure, enzymes
• Lipids (fats) → fatty acids + glycerol → long-term energy
• Nucleic acids → DNA/RNA → genetic material
35. Describe the structures of macromolecules
• Carbohydrates → monosaccharides (e.g., glucose) → linked sugars
• Proteins → chains of amino acids (peptide bonds)
• Lipids → triglycerides (glycerol + 3 fatty acids)
• Nucleic acids → nucleotides (sugar + phosphate + base)
36. Describe the process of the digestion of macromolecules
Carbohydrates:
• Broken down → glucose
Proteins:
• Broken down → amino acids
Lipids:
• Emulsified (bile) → digested → fatty acids
Nucleic acids:
• Broken into nucleotides
👉 Key idea:
Large → small = absorbable
37. Describe the location of digestion of macromolecules
Carbohydrates:
• Mouth (amylase)
• Small intestine
Proteins:
• Stomach (pepsin)
• Small intestine
Lipids:
• Mostly small intestine (lacteals)
Nucleic acids:
• Small intestine
38. Describe the important enzymes in their digestion
Carbohydrates:
• Salivary amylase
• Pancreatic amylase
Proteins:
• Pepsin (stomach)
• Proteases like trypsin and chymotrypsin (come from the pancreas)
Lipids:
• Pancreatic lipase
Nucleic acids:
• Nucleases
39. Describe the three classes of carbohydrates
• Sugars (simple carbs) → quick energy
• Starch (complex carbs) → stored glucose
• Fiber → not digested → helps movement
40. Describe proteins
Made of amino acids
Functions:
• Structure
• Enzymes
• Repair
• Hormones
• Fluid balance
Digestion:
• Broken into amino acids
Excess amino acids:
• Deamination (removal of an amino acid group) – occurs in the liver and urea is eliminated
41. Describe lipids
Made of fatty acids + glycerol
Functions:
• Long-term energy storage
• Insulation
Digestion:
• Bile → emulsifies
• Lipase → breaks down
Absorption:
• Lacteals (lymph) then it enters the bloodstream (fats are too large to enter blood capillaries directly)
42. Describe nucleic acids
DNA and RNA
Made of nucleotides
Digested into:
• Nitrogen bases
• Sugars
• Phosphates
Occurs in:
• Small intestine
🚨 DIGESTIVE SYSTEM — what SHE emphasized (from your lectures)
🔥 1. SMALL INTESTINE = MOST IMPORTANT ORGAN
She emphasized this multiple times
👉 Know:
~90% digestion + absorption happens here
WHY:
Circular folds
Villi
Microvilli
👉 Translation (how she tests):
“Where does most absorption occur?”
“Why is the small intestine so efficient?”
🔥 2. FAT DIGESTION (VERY HIGH-YIELD — SHE REPEATED THIS)
Steps (know in order):
Bile (from liver)
Emulsifies fat
NOT an enzyme
Pancreatic lipase
Digests fat
Absorption
Fats → lacteals (lymph)
Then → bloodstream
👉 She will ask this indirectly:
“Why does lymph flow increase after a fatty meal?”
✔ Because fats enter lacteals
🔥 3. CCK (SHE CLEARLY EMPHASIZED THIS HORMONE)
👉 Released from:
Duodenum
👉 Function:
Contracts gallbladder
Releases bile
Stimulates pancreatic enzymes
👉 Expect:
“What triggers bile release?”
✔ CCK
🔥 4. PANCREAS (REPEATED FUNCTION)
👉 Know:
Releases:
Amylase (carbs)
Lipase (fats)
Proteases (proteins)
Bicarbonate
👉 Bicarbonate:
Neutralizes stomach acid
🔥 5. STOMACH — HCl FUNCTIONS (SHE EMPHASIZED THIS)
👉 Hydrochloric acid:
Activates pepsin
Denatures proteins
Kills microbes
👉 She likes this as a multi-answer concept
🔥 6. PERISTALSIS vs SEGMENTATION (SHE LIKES THIS DISTINCTION)
Peristalsis → movement forward
Segmentation → mixing
👉 Simple but she will twist wording
🔥 7. DIGESTION PURPOSE (FOUNDATION — SHE REPEATED)
👉 Big idea:
Large molecules cannot cross membranes
So:
Carbs → glucose
Proteins → amino acids
Fats → fatty acids
👉 Expect:
“Why is digestion necessary?”
🔥 8. LIVER + GALLBLADDER (LINKED CONCEPT)
Liver → makes bile
Gallbladder → stores bile
👉 Released when:
CCK is present
🔥 9. ABSORPTION PATHWAYS (IMPORTANT CONNECTION)
Most nutrients → blood
Fats → lymph first (lacteals)
👉 She connects this to:
Nutrition
Circulation
🔥 10. MOTILITY + DIGESTION INTEGRATION
She tied this together conceptually:
Motility → moves + mixes
Enzymes → chemically break down
Surface area → absorbs
👉 This is how she builds multi-step questions
CHAPTER 27 — NUTRITION
1. Compare / contrast macronutrients
Provide energy (calories)
Types:
• Carbohydrates
• Lipids
• Proteins
👉 Main role: fuel for ATP
2. Compare / contrast micronutrients
Do NOT provide energy
Types:
• Vitamins
• Minerals
👉 Main role: regulation of body processes
3. Compare / contrast essential nutrients
• Must be obtained from diet
• Body cannot make them
4. Compare / contrast non-essential nutrients
• Body can synthesize them
• Not required from diet
5. Describe the major categories of macronutrients (digestion + use)
Carbohydrates:
• Digestion = broken down into glucose
• Use = primary source of energy + used to produce ATP + stored as glycogen
Lipids:
• Digestion = emulsified by bile + broken down by lipase
• Use = long-term energy storage + insulation and protection + can be converted to acetyl-CoA for ATP
Proteins:
• Digestion = broken down into amino acids
• Use = build and repair tissue + enzymes, hormones, immune function + can be used for energy after deamination
7. Identify dietary sources and examples
Carbohydrates:
• Sugar → fruit, sweets
• Starch → bread, rice
• Fiber → vegetables, whole grains
Lipids:
• Triglycerides → oils, butter
• Saturated fats → animal fats
• Unsaturated fats → plant oils
• Polyunsaturated → fish oils
• Cholesterol → animal products
Proteins:
• Complete (has all the essential 9 amino acids present) → quinoa (planted based), eggs (animal-based)
• Incomplete (missing one of more essential animo acid) → most plant sources, such as beans lentils, peanuts rice, wheat, corn, oats
8. Compare / contrast water-soluble vitamins
• Dissolve in water
• Not stored
• Need regular intake
• Eg: Vitamin C and any B vitamins
9. Compare / contrast how water-soluble vitamins function
• Act as coenzymes
• Help metabolic reactions
10. Compare / contrast fat-soluble vitamins
• Vitamins A, D, E, K
• Absorbed with fats
• Stored in body
11. Compare / contrast how fat-soluble vitamins function
• They are absorbed with fats and transported through lymph (lacteals)
• They are stored in the body (mainly liver and adipose so they don’t need to be consumed daily
A = vision
D = calcium – bones
E = antioxidants
K = clotting
12. Identify important minerals and functions
• Iron → oxygen transport (hemoglobin)
• Calcium → bones, muscle contraction
• Sodium / potassium → nerve signals, fluid balance
• Iodine → thyroid hormones
• Zinc → enzyme function, immunity
13. List the MyPlate items included in a food label
• ½ plate → Fruits + Vegetables
• ¼ plate → Grains (preferably whole grains)
• ¼ plate → Protein
• + Dairy on the side
14. Compare / contrast fed (absorptive) state
• Occurs after eating
• Insulin dominant
• Nutrients stored
15. Compare / contrast how fed state is regulated
Insulin (this is when blood sugar is too high):
• Increases glucose uptake into cells
• Increases glycogen storage
16. Compare / contrast fasting (postabsorptive) state
• Occurs between meals
• Glucagon dominant
• Energy released
17. Compare / contrast how fasting state is regulated
Glucagon (this is when blood sugar is too low)
• Glycogenolysis which takes place in the liver needs to occur, which is breaking glycogen into glucose
• Releases glucose into bloodstream
18. Compare / contrast cholesterol synthesis in the liver
• Liver produces cholesterol
Used for:
• Cell membranes
• Hormones
19. Describe the transport of lipids within the blood
• Lipids transported as lipoproteins
Fats absorbed via:
• Lacteals → lymph → bloodstream
20. Understand how nutrients enter cellular respiration
Carbohydrates
• Broken down into glucose
• Glucose enters glycolysis then continues through intermediate, citric and electron
• Carbs enter at the very beginning
Lipids
• Broken down into fatty acids
• Fatty acids are converted into acetyl-CoA
• Enters at the citric acid level
Proteins
• Broken down into amino acids
• Undergo deamination
• Then enters as pyruvate or enters a section of the citric acid cycle (it can enter at different points of this cycle)
🔥 MOST LIKELY TESTED
1. Fed vs Fasting State (VERY HIGH-YIELD)
Fed (absorptive)
Hormone: insulin
Effect:
Glucose enters cells
Glycogen stored
Fasting (postabsorptive)
Hormone: glucagon
Effect:
Glycogen → glucose (glycogenolysis)
Glucose released into blood
👉 She will NOT ask definition
👉 She WILL ask:
“after a meal what happens?”
“low blood glucose → what pathway activates?”
2. Insulin vs Glucagon (CORE MECHANISM)
Insulin → lowers blood glucose
Glucagon → raises blood glucose
👉 MUST know:
Where glucose is going
Where it’s coming from
3. Lipid transport (ties to digestion)
👉 This is a crossover topic she likes
Fats absorbed → lacteals (lymph)
Then → bloodstream
👉 Expect:
“why don’t fats go directly into blood?”
4. Macronutrients → where they go
She connects this to respiration
Carbs → glycolysis
Fats → acetyl-CoA
Proteins → Krebs
👉 This is integration question territory
5. Complete vs Incomplete proteins
You already caught this ✔
👉 Expect:
Definition
Possibly:
Eggs
Quinoa
6. Water vs Fat-soluble vitamins
She won’t go deep—but:
Know:
Water-soluble:
B + C
Not stored
Fat-soluble:
A, D, E, K
Stored
Absorbed with fat
👉 She may connect this to:
Fat digestion
7. Fat absorption connection
👉 This overlaps with digestion (VERY important)
Bile → emulsifies fat
Lipase → digests
→ lacteals → lymph