Citric acid cycle (carbohydrate metabolism II)

name the 8 major molecules of the citric acid cycle

oxaloacetate, citrate, isocitrate, alpha ketoglutarate, succinyl coa, succinate, fumarate and malate

an intermediate in the conversion of citrate to isocitrate

aconitate

compound derived from aconitate by aconitate decarboxylase

itaconate

which enzyme catalyses the formation of citrate from water, acetyl coa and oxaloacetate?

citrate synthase

which enzyme catalyses the isomerization reaction from citrate to isocitrate

aconitase

which enzyme catalyses the formation of itaconate from aconitate?

aconitate decarboxylase

which enzyme catalyses the oxidative decarboxylation of isocitrate to alpha ketoglutarate

isocitrate dehydrogenase

which enzyme catalyses the oxidative decarboxylation of alpha ketoglutarate to succinyl coa

alpha ketoglutarate dehydrogenase

what bond is present between the succinyl group and coenzyme a?

thioester bond

which enzyme catalyses the conversion of succinyl coa to succinate?

succinyl coa synthetase

what is a side product of succinyl coa synthetase catalysing the conversion of succinyl coa to succinate?

GTP

what enzyme catalyses the conversion of succinate to fumarate

succinate dehydrogenase

which hydrogen carrier receives the hydrogen lost from the reaction involving succinate dehydrogenase?

FAD

which enzyme catalyses the hydration reaction converting fumarate to malate?

fumarase

which enzyme catalyses the dehydration reaction converting malate to oxaloacetate?

malate dehydrogenase

which two molecules undergo oxidative decarboxylation?

isocitrate and alpha ketoglutarate

which two molecules (including their origins) fuel brown fat thermogenesis?

exogeneous itaconate and muscle derived succinate

which molecules inhibit pyruvate dehydrogenase?

ATP, NADH and acetyl CoA

which molecules inhibit alpha ketoglutarate dehydrogenase?

ATP, NADH and succinyl CoA

which molecules inhibit isocitrate dehydrogenase?

ATP and NADH

which molecule stimulates isocitrate dehydrogenase?

ADP