PTCB Prt 3- High Alert Medications

IV adrenergic agonists

Epinephrine, phenylephrine, norepinephrine

IV adrenergic antagonists

propranolol, metoprolol, labetalol

Anesthetic agents

Propofol, Ketamine

Anti-thrombotic Agents

• Anticoagulants: warfarin, Low molecular wieght heparin, unfractionated heparin

• DOACs & Factor Xa inhibtors: rivaroxaban; fondaparinux

• Direct Thrombin Inhibitors: argatroban, bivalirudin, dabigatran

• Glycoprotein IIb/IIIa Inhibitors: epifibatide

• Thrombolytics: alteplase, reteplase, tenecteplase

IV Antiarrhythmics

Amiodarone

Chemotherapy agents

methotrexate

Hypertonic Solutions

Dextrose solutions that are >/=20%

IV sodium chloride >0.9%

Renal Solutions such as…

Dialysis solutions both peritoneal and hemodialysis

Anti-diabetic Agents

• Oral hypoglycemic agents: glyburide, glimepiride, metformin

• Insulin

IV inotropic agents

digoxin

Liposomal formulations

liposomal amphotericin B

Narcotics/opioids

oxycodone, hydrocodone, hydromorphone

Neuromuscular blocking agents

succinylcholine, rocuronium, vecuronium

Sedation agents

chloral hydrate, midazolam, dexmedetomidine

Certain Methods of administration of medications

• Epidural administration of any medication

• Intrathecal administration of any medication

Specific IV medications

1. IV nitroprusside sodium - used to lower dangerously high blood pressure

2. IV potassium chloride or potassium phosphate- helps to restore the electrical balance within and around cells. This is particularly important for the proper function of cardiac and skeletal muscles

3. IV Vasopressin- to help raise dangerously low blood pressure

4. IV radiocontrast agents

Broad categories

1. Chemotherapy agents (ex: methotrexate)

2. Parenteral nutrition

3. Sterile water for injection, inhalation and irrigation in containers of >/= 100mL