CPP LAB [ADE]

ACE Inhibitors

Dry, nonproductive cough

ACE Inhibitors

Angioedema (swelling)

ACE Inhibitors

Hyperkalemia (elevated potassium levels)

• ACE Inhibitors

• Atenolol

Hypotension (low blood pressure) [2]

ACE Inhibitors

Reversible decline in kidney function

ACE Inhibitors

Cholestatic jaundice

ACE Inhibitors

Hepatitis

• Thalidomide

• Warfarin

• Isotretinoin

• Lithium

• Tetracycline

• Valproic Acid

• Methimazole

Teratogenic effects (birth defects)

Mnemonic: "TWILT-VM"

• Thalidomide

• Ethanol

Peripheral neuropathy (nerve damage) [2]

• Thalidomide

• Diazepam

Sedation (drowsiness) [2]

Thalidomide

Constipation

• Penicillamine

• Phenytoin

• Methimazole

Rash

Mnemonic: PePheMe

Penicillamine

Taste disturbances

Penicillamine

Proteinuria (presence of protein in urine)

• Penicillamine

• Valproic Acid

• Thrombocytopenia (low platelet count) [2]

Penicillamine

Autoimmune reactions (e.g., myasthenia gravis)

Tetracycline

Photosensitivity (increased sensitivity to sunlight)

• Tetracycline

• Ethanol

• Lithium

• Methimazole

• Misoprostol

• Ibuprofen

• Alendronate

Gastrointestinal distress [7]

Mnemonic: T.E.L. Me.M.I.A.

Tetracycline

Esophageal ulceration and strictures

Tetracycline

Teeth discoloration

• Tetracycline

• Methimazole

• Isotretinoin

• Valproic Acid

• Ethanol

Hepatotoxicity (liver toxicity) [5]

Mnemonic: TeMI-VE"

Tetracycline

Calcifications

Ethanol

Liver damage (e.g., cirrhosis)

Ethanol

Addiction

Ethanol

Impaired judgment

Ethanol

Neurological impairments (e.g., neuropathy)

• Ethanol

• Prednisone

Cardiovascular issues (e.g., hypertension) [2]

• Lithium

• Ibuprofen

• Methimazole

• Misoprostol

• Alendronate

Gastrointestinal upset (e.g., nausea, diarrhea) [5]

Mnemonic: "LiMMIA"

• Lithium

• Valproic Acid

Tremors[2]

Lithium

Polyuria (frequent urination)

Lithium

Hypothyroidism (underactive thyroid)

• Lithium

• Valproic Acid

• Prednisone

• Tibolone

Weight gain[4]

Mnemonic: "L.V.P.T.

Lithium

Acne

Lithium

Thinning hair

Lithium

Toxicity symptoms: lethargy, slurred speech, muscle weakness, ataxia, confusion, ECG changes

Methimazole

Agranulocytosis (a serious drop in white blood cells)

Methimazole

Arthralgia (joint pain)

Methimazole

Fever

• Warfarin

• Ibuprofen

Bleeding [2]

Warfarin

Nasal hypoplasia

Warfarin

Hypoplasia of extremities

Warfarin

Cardiac defects

Warfarin

Scoliosis

Warfarin

Mental retardation

Warfarin

Skin necrosis

Warfarin

Purple toe syndrome

• Phenytoin

• Prednisone

• Warfarin

Osteoporosis with long-term use

Mnemonic: PPW

Isotretinoin

Dry skin and mucous membranes

Isotretinoin

Elevated lipid levels

• Lithium

• Isotretinoin

• Prednisone

• Atenolol

Mood changes (e.g., depression) [4]

Mnemonic: LIPAt

• Isotretinoin

• Alendronate

Musculoskeletal pain [2]

Misoprostol

Diarrhea

• Misoprostol

• Tibolone

Abdominal cramping [2]

Misoprostol

Uterine contractions (can induce labor)

Misoprostol

Headache

Phenytoin

Gingival hyperplasia (gum overgrowth)

Phenytoin

Ataxia (loss of coordination)

Phenytoin

Hirsutism (excessive hair growth)

Phenytoin

Nystagmus (involuntary eye movement)

Valproic Acid

Pancreatitis (inflammation of the pancreas)

Ibuprofen

Increased risk of bleeding

Ibuprofen

Renal impairment with long-term use

Ibuprofen

Cardiovascular risks (e.g., heart attack, stroke)

Prednisone

Increased susceptibility to infections

Prednisone

Hyperglycemia (elevated blood sugar levels)

Prednisone

Hypertension (high blood pressure)

Prednisone

Mood swings

Prednisone

Cataracts

Diazepam

Drowsiness

Diazepam

Potential for dependence

Diazepam

Muscle weakness

Diazepam

Respiratory depression at high doses

Diazepam

Cognitive impairment

Diazepam

Paradoxical reactions (e.g., agitation)

Atenolol

Bradycardia (slow heart rate)

Atenolol

Fatigue

Atenolol

Cold extremities

• Atenolol

• Teriparatide

Dizziness [2]

Teriparatide

Nausea

Teriparatide

Potential risk of osteosarcoma (a type of bone cancer)

• Teriparatide

• Raloxifene

Leg cramps [2]

Teriparatide

Hypercalcemia (elevated calcium levels)

Raloxifene

Hot flashes

Raloxifene

Increased risk of venous thromboembolism (blood clots)

Raloxifene

Peripheral edema (swelling)

Tibolone

Abdominal pain

Tibolone

Breast tenderness

Tibolone

Vaginal bleeding

Tibolone

Endometrial changes

• Tibolone

• Alendronate

Atypical femoral fractures [2]

Alendronate

Rare instances of osteonecrosis of the jaw

Alendronate

Hypocalcemia (low calcium levels)