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These flashcards cover essential vocabulary and definitions required for mastering topics in Applied Physiology, aiding in review for the exam.
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homeostasis
The maintenance of stable internal conditions in the body.
metabolism
The sum of all chemical reactions that occur in the body.
physiology
The study of the body's functions and processes.
anabolism
The metabolic process that builds larger molecules from smaller ones.
catabolism
The metabolic process that breaks down larger molecules into smaller ones.
enzyme
A protein that acts as a catalyst to speed up biochemical reactions.
substrate-level phosphorylation
The direct production of ATP by transferring a phosphate group to ADP from a phosphorylated intermediate.
aerobic respiration
A process that requires oxygen to produce ATP.
anaerobic respiration
A process that does not require oxygen to produce ATP.
nerve impulse
An electrical signal that travels along the axon of a neuron.
action potential
A rapid change in membrane potential that propagates along the membrane of a neuron.
refractory period
The time following an action potential during which a neuron cannot initiate another action potential.
ligand
A molecule that binds to a specific site on a protein, such as a receptor.
receptor
A protein that detects specific signals in the body's environment.
negative feedback
A process that reverses a change in a controlled condition.
positive feedback
A process that amplifies changes in a controlled condition.
transepithelial transport
The movement of substances across epithelial cells.
osmolarity
A measure of the concentration of solute particles in a solution.
tonicity
The effect of a solution on the shape of cells.
isotonic solution
A solution that has the same osmolarity as body fluids.
hypotonic solution
A solution that has a lower osmolarity than body fluids.
hypertonic solution
A solution that has a higher osmolarity than body fluids.
concentration gradient
The difference in concentration of a substance across a space.
diffusion
The passive movement of molecules from an area of higher concentration to an area of lower concentration.
facilitated diffusion
The process of passive transport of molecules across a membrane via protein channels.
active transport
The movement of molecules against their concentration gradient, requiring energy.
coenzyme
A non-protein organic molecule that aids in enzyme function.
cell membrane
The semi-permeable barrier surrounding the cell.
phospholipid bilayer
A double layer of phospholipids that makes up cell membranes.
chromatin
The material of which the chromosomes of organisms are composed.
thromboxanes
A group of eicosanoids that promote platelet aggregation.
prostaglandins
Lipids made at sites of tissue damage or infection.
second messenger
A molecule that relays signals received at receptors on the cell surface.
cyclic AMP (cAMP)
A second messenger used in signaling pathways.
adenylate cyclase
An enzyme that converts ATP to cyclic AMP.
G-protein
A molecular switch that transmits signals from receptors to target proteins.
diacylglycerol (DAG)
A second messenger that activates protein kinase C.
Ca2+
Calcium ion, critical for various cellular functions including muscle contraction.
exocytosis
The process of vesicle fusion with the plasma membrane to release substances outside the cell.
endocytosis
The process by which cells internalize substances from their external environment.
synapse
The junction between two neurons where communication occurs.
neurotransmitter
Chemicals that transmit signals across a synapse.
signal transduction
The process by which a cell responds to signals from outside.
epithelium
Layers of cells that cover the surfaces of the body and line cavities.
sarcoplasmic reticulum
An organelle that stores calcium ions in muscle cells.
muscle twitch
A single contraction of muscle fibers in response to a stimulus.
tetanic contraction
A sustained muscle contraction resulting from frequent stimulation.
fatigue
Inability of a muscle to maintain its strength of contraction.
hypertrophy
Increase in muscle size due to exercise.
atrophy
Decrease in muscle size due to unused or inactivity.
hemoglobin
A protein in red blood cells that carries oxygen.
erythropoiesis
The production of red blood cells.
hypoxemia
Low levels of oxygen in the blood.
histamine
A chemical released during inflammatory responses.
depolarization
A decrease in the difference between the inside and outside of the cell membrane.
hyperpolarization
An increase in the difference between the inside and outside of the cell membrane.
potassium channel
A type of ion channel that allows K+ ions to flow in and out of cells.
sodium channel
A type of ion channel that allows Na+ ions to flow in and out of cells.
acetylcholine
A neurotransmitter that transmits signals in the nervous system.
muscle fiber
A single muscle cell.
myofilaments
Contractile proteins within muscle cells.
troponin
A protein that binds calcium ions and facilitates muscle contraction.
tropomyosin
A protein that blocks actin binding sites in muscle fibers.
muscle spindle
Sensory receptors within the belly of muscles that detect changes in muscle length.
Golgi tendon organ
Sensory receptors that sense changes in muscle tension.
endomysium
The connective tissue surrounding each muscle fiber.
perimysium
The connective tissue surrounding a group of muscle fibers (fascicle).
epimysium
The connective tissue surrounding the entire muscle.
threshold potential
The membrane potential that must be reached for an action potential to occur.
graded potential
A change in membrane potential that varies in size.
autonomic nervous system
The part of the nervous system that controls involuntary actions.
somatic nervous system
The part of the nervous system that controls voluntary actions.
dendrites
Branch-like structures that receive signals from other neurons.
axon
The long, thin part of a neuron that transmits impulses away from the cell body.
transduction
The process of converting one form of energy into another.
glutamate
An important excitatory neurotransmitter in the brain.
GABA (Gamma-Aminobutyric Acid)
An important inhibitory neurotransmitter in the brain.
glycolysis
The metabolic pathway that converts glucose into pyruvate.
Krebs cycle
A sequence of reactions in cellular respiration that produces NADH and FADH2.
catalyst
A substance that increases the rate of a chemical reaction.
feedback loop
A system structure that controls the output of a system.
permeability
The ability of substances to pass through a membrane.