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Underlying cause of nausea/vomiting
Determines which medication will be most effective.
First-line treatment for undifferentiated nausea and vomiting
Ondansetron 4-8 mg ODT or IV (rarely IM).
Conditions causing vestibular nausea
Motion sickness, vertigo, aeromedical evacuation.
Ineffectiveness of ondansetron in vestibular nausea
Different neurotransmitter pathways are involved.
Preferred drug for vestibular nausea
Prochlorperazine 12.5 mg IM.
Examples of prophylactic antiemetics usage
Spinal immobilisation, penetrating eye trauma.
Prophylactic drug and dose for nausea/vomiting
Ondansetron 4-8 mg ODT or IV.
Routes for ondansetron administration
Oral wafer (ODT), IV, rarely IM.
Main role of prochlorperazine in prehospital care
Treatment of vestibular nausea or when ondansetron is contraindicated.