New Drug Cards 2nd Week

Actos (Pioglitazone)

Class: Thiazolidinedione (TZD); Indication: Type 2 Diabetes; Dose: 15-45 mg once daily; ADRs: Weight gain, edema, heart failure worsening, fractures; Contra: NYHA III-IV heart failure, bladder cancer; BEERS: ⚠️ Use with caution (fluid retention); Controlled: No

Janumet / Janumet XR (Sitagliptin + Metformin)

Class: DPP-4 inhibitor + Biguanide; Indication: Type 2 Diabetes; Dose: XR once daily with food; ADRs: GI upset, lactic acidosis (rare); Contra: Severe renal impairment, metabolic acidosis; BEERS: ⚠️ Metformin—renal caution; Controlled: No

Farxiga (Dapagliflozin)

Class: SGLT-2 inhibitor; Indications: Type 2 Diabetes, Heart Failure, CKD; Dose: 5-10 mg once daily; ADRs: UTIs, genital yeast infections, dehydration; Contra: Severe renal disease, DKA; BEERS: ⚠️; Controlled: No

Jardiance (Empagliflozin)

Class: SGLT-2 inhibitor; Indication: Type 2 Diabetes, CV risk reduction; Dose: 10-25 mg once daily; ADRs: UTIs, hypotension, dehydration; Contra: Severe renal impairment; BEERS: ⚠️; Controlled: No

Invokana (Canagliflozin)

Class: SGLT-2 inhibitor; Indication: Type 2 Diabetes; Dose: 100-300 mg once daily; ADRs: UTIs, dehydration, ↑ amputation risk; Contra: Severe renal disease; BEERS: ⚠️; Controlled: No

Tradjenta (Linagliptin)

Class: DPP-4 inhibitor; Indication: Type 2 Diabetes; Dose: 5 mg once daily; ADRs: URI symptoms, pancreatitis (rare); Contra: Hypersensitivity; BEERS: ✅ Preferred (no renal adjustment); Controlled: No

Januvia (Sitagliptin)

Class: DPP-4 inhibitor; Indication: Type 2 Diabetes; Dose: 25-100 mg once daily (renal adjust); ADRs: Pancreatitis (rare); Contra: Severe renal impairment; BEERS: ⚠️; Controlled: No

Victoza (Liraglutide)

Class: GLP-1 receptor agonist; Indications: Type 2 Diabetes, CV risk reduction; Dose: 0.6 → 1.2 → 1.8 mg SC daily; ADRs: Nausea, vomiting, weight loss; Contra: Thyroid cancer, MEN2; BEERS: ⚠️; Controlled: No

Ozempic (Semaglutide - SC)

Class: GLP-1 receptor agonist; Indication: Type 2 Diabetes; Dose: 0.25 → 0.5 → 1 mg SC weekly; ADRs: Nausea, vomiting, weight loss; Contra: Thyroid cancer, MEN2; BEERS: ⚠️; Controlled: No

Trulicity (Dulaglutide)

Class: GLP-1 receptor agonist; Indication: Type 2 Diabetes; Dose: 0.75-1.5 mg SC weekly; ADRs: Nausea, diarrhea; Contra: Thyroid cancer, MEN2; BEERS: ⚠️

Controlled: No

Humalog (Insulin Lispro)

Class: Rapid-acting insulin; Indication: Diabetes mellitus; Dose: Mealtime dosing (individualized); ADRs: Hypoglycemia; BEERS: ✅ Safe; Controlled: No

Novolog (Insulin Aspart)

Class: Rapid-acting insulin; Indication: Diabetes mellitus; Dose: Mealtime dosing; ADRs: Hypoglycemia; BEERS: ✅ Safe; Controlled: No

Basaglar / Lantus / Toujeo (Insulin Glargine)

Class: Long-acting insulin; Indication: Diabetes mellitus; Dose: Once daily SC; ADRs: Hypoglycemia; Note: Toujeo = concentrated; BEERS: ✅ Safe; Controlled: No

Levemir (Insulin Detemir)

Class: Long-acting insulin; Indication: Diabetes mellitus; Dose: Once or twice daily SC; ADRs: Hypoglycemia; BEERS: ✅ Safe; Controlled: No

Tresiba (Insulin Degludec)

Class: Ultra-long-acting insulin; Indication: Diabetes mellitus; Dose: Once daily SC (flexible timing); ADRs: Hypoglycemia; BEERS: ✅ Safe; Controlled: No

Zetia (Ezetimibe)

Class: Cholesterol absorption inhibitor

Indication: Hyperlipidemia (↓ LDL)

Dose: 10 mg once daily

ADRs: Diarrhea, myalgia, fatigue

Contra: Active liver disease (with statins)

BEERS: ✅ Safe

Controlled: No

Niaspan (Niacin ER)

Class: Antihyperlipidemic (vitamin B3)

Indication: Dyslipidemia (↑ HDL, ↓ TG)

Dose: 500-2000 mg once daily at bedtime

ADRs: Flushing, itching, hepatotoxicity, hyperglycemia

Contra: Active liver disease, peptic ulcer

BEERS: ⚠️ Use with caution (flushing, liver risk)

Controlled: No

Lovaza (Omega-3-Acid Ethyl Esters)

Class: Omega-3 fatty acid

Indication: Severe hypertriglyceridemia

Dose: 4 g/day (once or divided)

ADRs: Fishy taste, GI upset

Contra: Fish/shellfish allergy

BEERS: ✅ Safe

Controlled: No

Vascepa (Icosapent Ethyl)

Class: Omega-3 fatty acid (EPA only)

Indication: Hypertriglyceridemia, CV risk reduction

Dose: 2 g twice daily with food

ADRs: Arthralgia, bleeding risk

Contra: Fish/shellfish allergy

BEERS: ✅ Safe

Controlled: No

Lopid (Gemfibrozil)

Class: Fibrate

Indication: Hypertriglyceridemia

Dose: 600 mg twice daily (30 min before meals)

ADRs: GI upset, gallstones, myopathy

Contra: Severe liver/kidney disease

BEERS: ⚠️ Use with caution

Controlled: No

Cholestid (Colestipol)

Class: Bile acid sequestrant

Indication: Hyperlipidemia

Dose: Tablets or granules (varies)

ADRs: Constipation, bloating

Contra: Bowel obstruction

BEERS: ⚠️ Constipation risk

Controlled: No

Tricor (Fenofibrate)

Class: Fibrate

Indication: Hypertriglyceridemia

Dose: 48-145 mg once daily

ADRs: Myopathy, ↑ LFTs

Contra: Severe renal/hepatic disease

BEERS: ⚠️ Renal caution

Controlled: No

Questran (Cholestyramine)

Class: Bile acid sequestrant

Indication: Hyperlipidemia, pruritus

Dose: Powder packets mixed with liquid

ADRs: Constipation, bloating

Contra: Complete biliary obstruction

BEERS: ⚠️ Constipation risk

Controlled: No

Kristalose / Enulose (Lactulose)

Class: Osmotic laxative

Indications: Constipation, hepatic encephalopathy

Dose: 15-30 mL daily (titrate)

ADRs: Diarrhea, bloating

Contra: Galactose intolerance

BEERS: ⚠️ Dehydration risk

Controlled: No

Linzess (Linaclotide)

Class: GC-C agonist

Indication: IBS-C, chronic constipation

Dose: 72-290 mcg once daily

ADRs: Diarrhea

Contra: Children <6, bowel obstruction

BEERS: ⚠️ Diarrhea risk

Controlled: No

Prevacid (Lansoprazole)

Class: Proton pump inhibitor

Indications: GERD, ulcers

Dose: 15-30 mg once daily

ADRs: C. diff, ↓ Mg, fractures

Contra: Hypersensitivity

BEERS: ⚠️ Long-term use

Controlled: No

Dexilant (Dexlansoprazole)

Class: Proton pump inhibitor

Indication: GERD

Dose: 30-60 mg once daily

ADRs: Diarrhea, headache

Contra: Hypersensitivity

BEERS: ⚠️ Long-term use

Controlled: No

Protonix (Pantoprazole)

Class: Proton pump inhibitor

Indication: GERD, erosive esophagitis

Dose: 40 mg once daily

ADRs: C. diff, ↓ Mg

Contra: Hypersensitivity

BEERS: ⚠️ Long-term use

Controlled: No

Nexium (Esomeprazole)

Class: Proton pump inhibitor

Indication: GERD

Dose: 20-40 mg once daily

ADRs: Headache, diarrhea, fractures

Contra: Hypersensitivity

BEERS: ⚠️ Long-term use

Controlled: No

Carafate (Sucralfate)

Class: GI mucosal protectant

Indication: Duodenal ulcers

Dose: 1 g four times daily (empty stomach)

ADRs: Constipation

Contra: Severe renal impairment

BEERS: ⚠️ Aluminum accumulation

Controlled: No