* rupture or membranes prior to onset of labour regardless of gestational age
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* Preterm PROM (pPROM) – rupture of membranes before 37 weeks gestation
* Predisposing factors- maternal nutritional deficiencies, substance use, placental abruption, polyhydramnios, multiple pregnancy, prior preterm birth or PPROM, infections \*\*primarily chorioamnionitis or trauma
* Once membranes rupture - risk of infection- chorioamnionitis. Usually caused by normal flora e.g. E coli