P12 immunology ab

immunopathological reaction mediated by IgE

atopy – Type I

immunopathological reaction mediated by IgG and IgM

– cytotoxic

reaction – Type II

immunopathological reaction mediated by immune complexes

Type III

immunopathological reaction mediated by cells

Type IV– delayed type hypersensitivity (DTH)

DTH

delayed type hypersensitivity

Components of immune system in

Type I of hypersensitivity:

IgE

Mast cells

Basophiles

Eosinophils

Components of immune system in

Type II of hypersensitivity:

IgM or IgG

Complement

Macrophages

NK cells

Components of immune system in

Type III of hypersensitivity:

IgG or IgM

Complement

Neutrophils

Components of immune system in

Type IV Hypersensitivity:

Th1 cells

Tc cells

Macrophages

Cytokines (IFN-γ)

ADCC

Antibody-dependent cell-mediated cytotoxicity

HDN

Haemolytic disease of the new-born

AIHA

Autoimmune hemolytic anemia

SLE

Systemic lupus erythematosus

ANA

Autoantibodies

RF

Rheumatoid factor

PEG

polyethylene glycol

DTH

Delayed-type Hypersensitivity

BCG

Bacille Calmette-Guérin

PPD

Purified Protein Derivate